Recurrent headache and migraine within the family

Abstract

The aim of this research was to determine risk for family appearance of the recurrent headache (non-migraine and migraine). The recurrent headache can be understood as being a heterogeneous state, consisting of some more, still not found, hereditary disposition factors which altogether, interacting with surrounding factors give the recognizable clinical picture. The current heredity concept suggests multifactor heredity. The research was conducted in Vojvodina, the Northern Province of Serbia. The population of Vojvodina is around 2 million people belonging to more than 20 different ethnic groups. During the 20 years period (1988-2008), 30363 children aged 3 to 17 years were tested, independent of the place of birth. The presence of headaches similar to those tested was compared among all the members of the family within three generations. Positive family data of the recurrent headaches was detected among 98,6% children with migraine headaches, 64,7% children with non- migraine headaches, and 32,4% children without recurrent headaches. The relation among the members of the nuclear family (contingency quotient of 0,429) is significantly stronger than the relation to the members of wider family (contingency quotient of 0,338). The probability of a child having the migraine headache, and not the non-migraine one, is 0,664 for a mother, 0,644 for a father, 0,411 for a father`s mother, - 0,175 for a mother`s mother, 0,165 for a mother`s father, and - 0,102 for a father`s father having similar recurrent headaches

Increased Familial Risk and Evidence of Genetic Factor in Migraine

“…DucrosA talked about Genetics of migraine, stated that family history of migraine is the most potent and consistent risk factor for migraine, with a two-to three fold greater risk of migraine among relatives of people with migraine compared with controls [23]. The relation among the members of the nuclear family (contingency quotient of 0.429) was significantly stronger than the relation to the members of wider family (contingency quotient of 0.338), as he studied Risk of the recurrent headache and migraine appearance within the family, These results go with ours as we also found high frequency of first degree relative affection of migraine [24].…”

Mothers’ resolution of their children’s diagnosis of cerebral palsy

“…Cerebralna paraliza je jedna od najčešćih fizič-kih smetnji koja utiče na funkcionalni razvoj dece i često je udružena sa stanjima kao što su mentalna retardacija i epilepsija [5,6]. S obzirom na kompleksnu prirodu CP i brojne teškoće u prihvatanju dijagnoze, cilj ovih prikaza jeste da predstavimo različite vidove majčinog odnosa prema detetovoj dijagnozi.…”