Recurrent hematuria: A rare presentation of leiomyosarcoma of the prostate

Loghmari, Ahmed; Othmane, Mouna Ben; Belkacem, Oussama; Bouassida, Khaireddine; Hmida, Wissem; Jaidane, Mehdi

doi:10.1016/j.amsu.2022.103634

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Although urinary frequency and urgency are commonly reported symptoms in patients with prostate leiomyosarcomas, recurrent hematuria and urinary retention have only been reported in a handful of isolated cases. In this case of a 61-year-old male with a strong smoking history and a normal PSA level, hematuria may be a rare obvious symptom that can delay its diagnosis [5]. This patient's unique symptoms of recurrent hematuria and acute urinary retention may be associated with either the malignancy or due to a multitude of other factors.…”

Section: Discussionmentioning

confidence: 91%

Recurrent Hematuria, Urinary Tract Infections, and Urinary Retention: A Rare Presentation of Prostate Leiomyosarcoma

Sagireddy,

Abramowitz,

Sagireddy

et al. 2023

Preprint

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Prostatic leiomyosarcoma is quite rare. There is little consensus on the best treatment for these aggressive tumors. They are most often characterized by obstructive lower urinary tract symptoms without an elevated serum prostate-specific antigen level. A high degree of skepticism may help in detecting them in a timely manner since they lack specific clinical or imaging features. It can be diagnosed by immunohistochemical staining as, seen in our patient. Despite the lack of definitive treatment options, innovative multimodal treatment strategies may significantly improve the prognosis of patients suffering from this tumor. This case report describes a leiomyosarcoma of the prostate with metastasis.

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Section: Discussionmentioning

confidence: 91%

Recurrent Hematuria, Urinary Tract Infections, and Urinary Retention: A Rare Presentation of Prostate Leiomyosarcoma

Sagireddy,

Abramowitz,

Sagireddy

et al. 2023

Preprint

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Leiomyosarcoma of the Prostate: Report of Two Cases and Review of the Literature

Bettaieb,

Keskes,

Llacer Moscardo

2024

Case Rep Oncol

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Introduction: Leiomyosarcoma (LMS) of the prostate is an extremely rare and aggressive tumor that presents with nonspecific signs and symptoms. Treatment guidelines are not yet established. Case Presentation: We report two cases of LMS of the prostate. The presenting symptom was hematuria, and diagnosis was ascertained through a transurethral resection of the prostate for the 2 patients. The treatment course consisted of three courses of chemotherapy with gemcitabine and docetaxel, radical prostatectomy, and postoperative radiation therapy for the first patient and three courses of gemcitabine and radiation therapy of the prostate and the whole pelvis for the second patient. The follow-up of our 2 patients was 9 and 12 months, respectively. Recurrence occurred 10 months after treatment completion for the second case. No recurrence was noticed in the first case. Conclusion: These two cases highlight the importance of a multimodal approach to yield the best outcomes.

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Recurrent hematuria: A rare presentation of leiomyosarcoma of the prostate

Cited by 2 publications

References 5 publications

Recurrent Hematuria, Urinary Tract Infections, and Urinary Retention: A Rare Presentation of Prostate Leiomyosarcoma

Recurrent Hematuria, Urinary Tract Infections, and Urinary Retention: A Rare Presentation of Prostate Leiomyosarcoma

Leiomyosarcoma of the Prostate: Report of Two Cases and Review of the Literature

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