2024
DOI: 10.1002/clt2.12396
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Recurrent tick bites induce high IgG1 antibody responses to α‐Gal in sensitized and non‐sensitized forestry employees in Luxembourg

Neera Chakrapani,
Kyra Swiontek,
Judith M. Hübschen
et al.

Abstract: BackgroundThe α‐Gal syndrome (AGS) is characterized by the presence of specific IgE‐antibodies to the carbohydrate galactose‐α‐1,3‐galactose (α‐Gal). Sensitization to α‐Gal has been associated with tick bites and individuals exposed to ticks have an elevated risk of sensitization. The aim of this study was to analyze IgG and IgE antibody responses to α‐Gal in a high‐risk cohort of forestry employees (FE) in Luxembourg.MethodsQuestionnaires and serum samples of FE from Luxembourg (n = 219) were retrospectively … Show more

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