Red and brown seaweeds extracts: A source of biologically active compounds

Sapatinha, M.; Oliveira, Ademir Kleber Morbeck de; Costa, S.; Pedro, S.; Gonçalves, Amparo; Mendes, Rogério; Bandarra, Narcisa M.; Pires, Carla

doi:10.1016/j.foodchem.2022.133453

Cited by 22 publications

(26 citation statements)

References 35 publications

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“…Although the comparison of extraction yield between different studies is difficult due to various methods and solvents used, our yield values were comparable with those of other studies. For example, G. gracilis ’ yield of extraction using hot water was 24.63% [ 50 ], being close to our yield of 25.4% after 80% v / v methanol extraction. In addition, our C. amentacea ’s extraction yield of 34.1% was similar to the yield of 31% of macroalgae after 50% v / v ethanol extraction [ 51 ].…”

Section: Resultssupporting

confidence: 80%

“…They also concluded that polyphenols’ identification from marine macroalgae presents many difficulties due to there being complex samples and polyphenols’ presence at low concentrations [ 64 ]. The differences in polyphenols’ determination between our study and other studies may be attributed to different factors such as geographical location and season of collection, as well as extraction and chemical analysis methods [ 50 , 51 , 56 ].…”

Section: Resultscontrasting

confidence: 69%

“…For example, their ethyl acetate extract had a TPC of ~65 mg GAE/dw [ 53 ]. Moreover, Sapatinha et al [ 50 ] demonstrated that G. gracilis extracts had TPCs from 28.2 to 50.73 mg GAE/dw, but they used different solvents than we did.…”

Section: Resultsmentioning

confidence: 72%

“…In that case, although the same solvent as ours was used, microwave extraction was carried out [ 57 ], a method completely different than that used in our study. In general, apart from the extraction method [ 50 , 53 ], several other factors may affect macroalgae’s TPC values, such as seasonality [ 57 ], local environmental conditions (e.g., salinity, nutrient availability, UV irradiation, and light), and geographical location [ 50 , 58 , 59 , 60 ].…”

Section: Resultsmentioning

confidence: 99%

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Antioxidant Activity and Inhibition of Liver Cancer Cells’ Growth of Extracts from 14 Marine Macroalgae Species of the Mediterranean Sea

Goutzourelas

Kevrekidis

Barda

et al. 2023

Foods

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Macroalgae exhibit beneficial bioactivities for human health. Thus, the aim of the present study was to examine the antioxidant and anticancer potential of 14 macroalgae species’ extracts, namely, Gigartina pistillata, Gigartina teedei, Gracilaria gracilis, Gracilaria sp., Gracilaria bursa pastoris, Colpomenia sinuosa, Cystoseira amentacea, Cystoseira barbata, Cystoseira compressa, Sargassum vulgare, Padina pavonica, Codium fragile, Ulva intestinalis, and Ulva rigida, from the Aegean Sea, Greece. The antioxidant activity was assessed using DPPH, ABTS•+, •OH, and O2•− radicals’ scavenging assays, reducing power (RP), and protection from ROO•-induced DNA plasmid damage assays. Moreover, macroalgae extracts’ total polyphenol contents (TPCs) were assessed. Extracts’ inhibition against liver HepG2 cancer cell growth was assessed using the XTT assay. The results showed that G. teedei extract’s IC50 was the lowest in DPPH (0.31 ± 0.006 mg/mL), ABTS•+ (0.02 ± 0.001 mg/mL), •OH (0.10 ± 0.007 mg/mL), O2•− (0.05 ± 0.003 mg/mL), and DNA plasmid breakage (0.038 ± 0.002 mg/mL) and exhibited the highest RP (RP0.5AU 0.24 ± 0.019 mg/mL) and TPC (12.53 ± 0.88 mg GAE/g dw). There was also a significant correlation between antioxidant activity and TPC. P. pavonica (IC50 0.93 ± 0.006 mg/mL) exhibited the highest inhibition against HepG2 cell growth. Conclusively, some of the tested extracts exhibited significant chemopreventive properties, and so they may be used for food products.

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Section: Resultssupporting

confidence: 80%

Section: Resultscontrasting

confidence: 69%

Section: Resultsmentioning

confidence: 72%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Antioxidant Activity and Inhibition of Liver Cancer Cells’ Growth of Extracts from 14 Marine Macroalgae Species of the Mediterranean Sea

Goutzourelas

Kevrekidis

Barda

et al. 2023

Foods

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“…The iron-chelating activity of each fraction was estimated by the method described by Sapatinha et al with modifications [ 25 ]. Briefly, 50 μL of each sample solution and 50 μL of 1 mM FeCl 2 were mixed.…”

Section: Methodsmentioning

confidence: 99%

Antioxidant Capacities and Enzymatic Inhibitory Effects of Different Solvent Fractions and Major Flavones from Celery Seeds Produced in Different Geographic Areas in China

Zhang

et al. 2022

Antioxidants

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To extend the application of celery (Apium graveolens L.) seeds, the antioxidant and enzymatic inhibitory activities of different fractions and their main flavones were investigated. The n-butanol fractions possessed the highest total phenolic content (TPC) and total flavonoid content (TFC) values. The n-butanol fractions from Northeast China samples exhibited the strongest free radical scavenging (DPPH IC50 = 20.27 μg/mL, ABTS IC50 = 15.11 μg/mL) and ferric reducing antioxidant power (FRAP 547.93 mg trolox (TE)/g) capacity, while those collected from Hubei China showed the optimal cupric reducing antioxidant capacity (CUPRAC) values (465.78 mg TE/g). In addition, the dichloromethane fractions from Jiangsu samples displayed a maximum Fe2+ chelating capacity (20.81 mg ethylene diamine tetraacetic acid (EDTA)/g). Enzyme level experiments indicated polyphenolic compounds might be the main hypoglycemic active components. Subsequently, the enzyme inhibitory activity of nine main flavones was evaluated. Chrysoeriol-7-O-glucoside showed better α-glucosidase inhibitory activity than others. However, apigenin showed the best inhibitory effect on α-amylases, while the presence of glycosides would reduce its inhibitory effect. This study is the first scientific report on the enzymatic inhibitory activity, molecular docking, and antioxidant capacity of celery seed constituents, providing a basis for treating or preventing oxidative stress-related diseases and hyperglycemia.

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Biogenic ZnO nanoparticles synthesized using Halimeda opuntia seaweed extract: A sustainable approach for promoting horse gram seed germination

Bhuvaneshwari,

Padmalochana,

Natarajan

et al. 2024

J Nanopart Res

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Red and brown seaweeds extracts: A source of biologically active compounds

Cited by 22 publications

References 35 publications

Antioxidant Activity and Inhibition of Liver Cancer Cells’ Growth of Extracts from 14 Marine Macroalgae Species of the Mediterranean Sea

Antioxidant Activity and Inhibition of Liver Cancer Cells’ Growth of Extracts from 14 Marine Macroalgae Species of the Mediterranean Sea

Antioxidant Capacities and Enzymatic Inhibitory Effects of Different Solvent Fractions and Major Flavones from Celery Seeds Produced in Different Geographic Areas in China

Biogenic ZnO nanoparticles synthesized using Halimeda opuntia seaweed extract: A sustainable approach for promoting horse gram seed germination

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