Red tattoo reactions

Bhardwaj, Sachin S.; Taylor, James S.

doi:10.1034/j.1600-0536.2003.00090.x

Cited by 37 publications

(25 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…One plausible explanation could be the release of tattoo pigment, containing cobalt, into extracellular space during immunization, triggering a granulomatous reaction. A similar mechanism was proposed for a 38-year-old man who developed a delayed type hypersensitivity reaction to red dye after red tattoo laser ablation [6]. The precise relationship, if any, between H1N1 vaccination and cutaneous granulomas remains unclear.…”

Section: Commentmentioning

confidence: 91%

Granulomatous Reaction Confined to Two Blue-ink Tattoos after H1N1 Influenza Vaccine

Marc¹,

Ler²,

Tonkovic-Capin³

et al. 2010

J Vaccin Vaccinat

View full text Add to dashboard Cite

A 33-year-old white female presented to dermatology clinic with a three-month history of swelling and itching of blue-ink tattoos over each of her deltoid muscles. These symptoms began within one week of receiving intramuscular H1N1 vaccine (Sanofi-Pasteur, multidose vial containing 0.01% thimerosal, lot number UP005AA with expiration date March 15th 2011) into the right deltoid muscle superior to the tattoo on the right deltoid. These tattoos were placed eight years prior at different tattoo parlors. The patient denied past cutaneous eruptions or history of sarcoidosis or other vaccines or tattoos during this period. Past medical history included depression treated with depakote and haloperidol; hysterectomy with right oophorectomy and obesity. No medications had changed in the previous four months. Social history included occasional alcohol use but no tobacco or intravenous drug abuse. Physical examination showed induration confined to the blue-ink containing skin of two tattoos over the patient's deltoid muscles ( Figure 1). Other tattoos containing black, red and yellow ink were not affected.Histology of the punch biopsy specimen revealed noncaseating granulomas containing fine black granules (Figure 2). Staining revealed no evidence of acid-fast bacilli or fungi. Pathohistological differential diagnosis was sarcoidosis versus granulomatous reaction to pigment granules.Workup for sarcoidosis included chest X-rays, pulmonary function testing, ophthalmological examination and angiotensin converting enzyme serum levels. All studies were within normal limits except for pulmonary function testing which revealed a moderate restrictive lung defect. The patient declined further workup, as well as referral to a pulmonologist. A diagnosis was made of granulomatous reaction confined to blue-ink tattoos possibly triggered by H1N1 vaccine. After failing a trial of clobetasol ointment twice daily the patient is currently well-controlled with intralesional injections of triamcinolone acetonide. CommentNoncaseating granulomas in patients with edema and pruritus of tattoos have been attributed to both sarcoidosis and delayed type hypersensitivity reactions.1 Sarcoidosis cannot be excluded even if foreign pigment is found in a biopsy site [1].Sarcoidosis is a common disorder of the lungs and skin with AbstractNoncaseating granulomas occur due to a hypersensitivity reaction to an exogenous antigen. The introduction of the H1N1 vaccine has been successful in disease prevention but we expand the current literature on possible adverse reactions to the vaccine to include granulomatous reactions.

show abstract

Section: Commentmentioning

confidence: 91%

Granulomatous Reaction Confined to Two Blue-ink Tattoos after H1N1 Influenza Vaccine

Marc¹,

Ler²,

Tonkovic-Capin³

et al. 2010

J Vaccin Vaccinat

View full text Add to dashboard Cite

show abstract

“…This is confirmed only in a few cases of the previous reported. 13 We would like to express our appreciation for the invaluable assistance given by Drs Francisco de la Rosa…”

Section: Discussionmentioning

confidence: 99%

Sarcoid granuloma on black tattoo

Morales-Callaghan¹,

Aguilar-Bernier²,

Martínez-García

et al. 2006

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

“…[10] Nearly, 53.9% of our patients had an allergy to red pigment which is similar to many other studies. [313233] Although reactions to red pigment is the most common, nuances of red such as pink, orange, violet, and Bordeaux are also associated with tattoo reactions. [32] Increased reactions among amateur tattoo, which was done roadside may be because of acrylic paints used by some of the artists.…”

Section: Discussionmentioning

confidence: 99%