Réduction embryonnaire: indications, techniques, impact psychologique

Fetal reduction of triplet pregnancy: one or two?

“…These results led to the consideration of reduction to a singleton. There are no specific studies in the literature on FR to one in trichorinic triplets, the only studies available cover the FR of multiple pregnancies in general . In the absence of conclusive data, it remains uncertain whether FR should be recommended and if so, if reduction to one rather than two provides a better outcome.…”

“…Reduction of triplet pregnancies to twins has been shown to reduce the rate of moderate prematurity from 66% to 35% and severe prematurity from 23.8% to 10% and to increase full‐term delivery rate from 10% to 57% . When it comes to FR to singletons for maternal or fetal reasons, moderate prematurity rate decreases to 15.5%, severe prematurity rate to 2.8% and 68% carry their pregnancy till term . These results led to the consideration of reduction to a singleton.…”

“…The use of assisted reproductive technology (ART) is becoming increasingly widespread and now involves 15% of all couples in industrialized countries . The progress made by this technique has been offset by the number of high‐order multiple pregnancies (≥3 fetuses) with uncertain outcome .…”

Multifetal Pregnancy Reduction in Quadruplets: Perinatal Outcome—Analysis of 20 Consecutive Cases

“…MFPR can be carried out abdominally at 11-14 weeks and vaginally at 7 to 8 weeks [5,10]. Historically many different techniques have been described in the literature like mechanical disruption, air embolisation, electrocautery etc.…”

“…The outcome after MFPR may be as good as unreduced twins [6][7][8]. Apart from reducing the risk of premature delivery and pregnancy loss, MFPR can also reduce the risk of maternal complications in HOMP [8][9][10]. Moreover, it does not increase the risk of congenital anomaly for the surviving fetuses [11].…”