Reference Range of Embryo Volume by 3-D Sonography Using the XI VOCAL Method at 7 to 10 + 6 Weeks of Pregnancy

Abstract

We sought to establish normative data for three-dimensional ultrasound (3DUS) first-trimester embryonic volume using the extended imaging virtual organ computer-aided analysis (XI VOCAL) technique. This cross-sectional study involved 64 normal pregnancies at 7 to 10 + 6 weeks' gestation. Embryonic volume was obtained on 3DUS using the XI VOCAL technique with manual outline of 10 sequential planes. The mean, median, standard deviation, and maximum and minimum values were obtained for each week calculated. Polynomial regression models adjusted by the determination coefficient (R(2)) were created to assess the correlation between embryonic volume and gestational age (GA) and crown rump length (CRL). The intraclass correlation coefficient (ICC) was used to calculate inter- and intraobserver reproducibility. Mean embryonic volume went from 0.20 cm(3) (range 0.10 to 0.89 cm(3)) to 5.12 cm(3) (range 2.90 to 5.98 cm(3)). Embryonic volume was strongly correlated with GA (R(2) = 0.84) and with CRL (R(2) = 0.87). There was a good inter- and intraobserver reproducibility of embryonic volume with ICC = 0.999 and 0.995, respectively. Reference range for 3DUS first-trimester embryonic volume using the XI VOCAL technique were generated for pregnancies at 7 to 10 + 6 weeks, with high inter- and intraobserver reproducibility.

Effect of micronized progesterone on fetal‐placental volume in first‐trimester threatened abortion

“…Recently, several volume measurements using XI VOCAL technique in the first trimester of pregnancy have been documented. Araujo J unior et al, 8 Nardozza et al, 14 and Florido et al 15 have previously shown that XI VOCAL is a valid, reliable, and repeatable technique for volume measurements of such structures in the first trimester of pregnancy. We also detected good and moderate degrees of agreement in the GS (ICC 5 0.97; 95% CI, 0.88-0.99), placenta (ICC 5 0.94; 95% CI, 0.76-0.99), and in the embryonic (ICC 5 0.67 (95% CI, 0.34-0.92) and amniotic sac (ICC 5 0.65; 95% CI, 0.41-0.91) volume measurements, respectively.…”

“…It can particularly measure the volume of complex objects easily and accurately. Using this technique in the first trimester of pregnancy was previously described in several studies, [8][9][10][11] and it is possible to detect placental and fetal volumes accurately at this gestational period.…”

Η προγνωστική αξία της 3d υπερηχογραφίας στην εκτίμηση του μεγέθους του όγκου στις νεοπλασίες του τραχήλου της μήτρας

“…(Εικόνα από http://medison.com.vn/vn/default/Cong-nghe/3dxi/XI-XI-VOCAL.aspx) Βιβλιογραφικά με την μέθοδο XI VOCAL έχει μελετηθεί ο εμβρυικός μηρός [126] , το άνω άκρο [127] , η καρδιά του εμβρύου [128] , ο λεκιθικός ασκός [129], το μέγεθος εμβρύου [130] , τα εμβρυικά νεφρά [131] . Επίσης από τον Barreto EQ, 2010 [132] έγινε σύγκριση των τριών πιο συχνών μεθόδων τρισδιάστατης μέτρησης δηλαδή της multiplanar , της VOCAL και της XI-VOCAL .…”