Reference standards for body fat measures using GE dual energy x-ray absorptiometry in Caucasian adults

Imboden, Mary T.; Welch, Whitney A.; Swartz, Ann M.; Montoye, Alexander H.K.; Finch, Holmes; Harber, Matthew P.; Kaminsky, Leonard A.

doi:10.1371/journal.pone.0175110

Cited by 103 publications

(75 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our sample, an AG ratio <1.0 presented with small variation in VAT, but with a strong, correlational increase in VAT when >1.0. This might imply that the mean AG ratios observed in our sample were within a healthy range, even when being above a previously suggested normative level (Imboden et al, ). Moreover, among the participants with BN and BED, 15% and 42%, respectively, had an AG ratio >1, and all but two of these had VAT levels above normative levels.…”

Section: Discussioncontrasting

confidence: 45%

“…All data were analyzed according to the guidelines (Nana, Slater, Stewart, & Burke, 2015). Recommended %BF for premenopausal females was set at <33%, based on an evaluation of previous studies (Imboden et al, 2017a;Okorodudu et al, 2010). By combining BMI and %BF information, we defined a woman as having "masked obesity" if BMI < 25 and %BF 33%.…”

Section: Physical Activity Crf and Muscle Strengthmentioning

confidence: 99%

See 1 more Smart Citation

Body composition and physical fitness in women with bulimia nervosa or binge‐eating disorder

Mathisen

Rosenvinge

Friborg

et al. 2018

Intl J Eating Disorders

View full text Add to dashboard Cite

ObjectiveKnowledge about physical fitness in women with bulimia nervosa (BN) or binge‐eating disorder (BED) is sparse. Previous studies have measured physical activity largely through self‐report, and physical fitness variables are mainly restricted to body mass index (BMI) and bone mineral density. We expanded the current knowledge in these groups by including a wider range of physical fitness indicators and objective measures of physical activity, assessed the influence of a history of anorexia nervosa (AN), and evaluated predictive variables for physical fitness.MethodPhysical activity, blood pressure, cardiorespiratory fitness (CRF), muscle strength, body composition, and bone mineral density were measured in 156 women with BN or BED, with mean (SD) age 28.4 years (5.7) and BMI 25.3 (4.8) kg m−2.ResultsLevel of physical activity was higher than normative levels, still <50% met the official physical activity recommendation. Fitness in women with BN were on an average comparable with recommendations or normative levels, while women with BED had lower CRF and higher BMI, VAT, and body fat percentage. We found 10–12% with masked obesity. A history of AN did not predict current physical fitness, still values for current body composition were lower when comparing those with history of AN to those with no such history.DiscussionOverall, participants with BN or BED displayed adequate physical fitness; however, a high number had unfavorable CRF and body composition. This finding calls for inclusion of physical fitness in routine clinical examinations and guided physical activity and dietary recommendations in the treatment of BN and BED.

show abstract

Section: Discussioncontrasting

confidence: 45%

Section: Physical Activity Crf and Muscle Strengthmentioning

confidence: 99%

Body composition and physical fitness in women with bulimia nervosa or binge‐eating disorder

Mathisen

Rosenvinge

Friborg

et al. 2018

Intl J Eating Disorders

View full text Add to dashboard Cite

show abstract

“…Percentage android fat for all subjects was determined by dual-energy x-ray absorptiometry. [18][19][20][21] Total android fat (total body fat) was calculated as the product of body weight and percentage android fat.…”

Section: Subjectsmentioning

confidence: 99%

Persistence of a Posaconazole‐Mediated Drug‐Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety

Chow¹,

Harmatz

Ryan³

et al. 2018

The Journal of Clinical Pharma

View full text Add to dashboard Cite

The antianginal agent ranolazine (Ranexa®) is metabolized primarily by cytochrome P450-3A (CYP3A) enzymes. Coadministration with strong CYP3A inhibitors, such as ketoconazole and posaconazole, is contraindicated due to risk of QT prolongation from high levels of ranolazine. This study evaluated the time course of recovery from the posaconazole drug interaction in normal-weight and otherwise healthy obese subjects. Subjects received single doses of ranolazine in the baseline control condition, again during coadministration of posaconazole, and at 4 additional time points during the 2 weeks after posaconazole discontinuation. With posaconazole coadministration, the geometric mean ratio of ranolazine area under the concentration curve (AUC) increased by a factor of 3.9 in normals and by 2.8 in obese subjects. Posttreatment washout of posaconazole was slow in normals (mean half-life 36 hours) and further prolonged in obese subjects (64 hours). Recovery of ranolazine AUC toward baseline was delayed. AUC remained significantly elevated above baseline in normal-weight and obese subjects for 7-14 days after stopping posaconazole. Current product labeling does not address the need for delay or a reduced dose of ranolazine after discontinuation of a strong CYP3A inhibitor before ranolazine can be safely administered. We recommend that administration of ranolazine should be limited to 500 mg twice daily for 7 days after posaconazole discontinuation in patients with body mass index 18.5-24.9 kg/m and for 12 days in patients with body mass index ≥35 kg/m after ranolazine is resumed.

show abstract

“…From VF measurements, we calculated the ratios VF/TBF, VF/weight, VF/LM, and VF/Android fat. Body composition parameters were analyzed using age‐, gender‐, race‐, and instrument‐specific reference values for VF, TBF, and LMI …”

Section: Methodsmentioning

confidence: 99%

Visceral fat, cardiometabolic risk factors, and nocturnal blood pressure fall in young adults with primary hypertension

Miazgowski

Taszarek

Miazgowski

2019

J of Clinical Hypertension

View full text Add to dashboard Cite

The aims of this study were to assess associations of body fat levels and distribution with metabolic profiles and 24-hour blood pressure in young adults with primary hypertension. Visceral fat (VF) was estimated using dual-energy X-ray absorptiometry.VF was highly significantly associated with a high frequency of overweight/obesity, impaired fasting glucose, increased levels of triglycerides and LDL-cholesterol, and lowered level of HDL-cholesterol. The value of systolic blood pressure (SBP) nocturnal fall was similar between patients receiving RAAS inhibitors, beta-blockers, and calcium channel blockers. In multiple regression, the VF/weight ratio after adjusting for age, gender, total fat, and chronotherapeutic drug delivery was associated with the percentage SBP nocturnal fall (β = −.3108; 95% CI: −0.5923; −0.0980; P = .013).In males, excess VF increased the odds by 2.3 times for non-dipping blood pressure.Our results suggest that in young adult hypertensives, the VF/weight ratio might be associated with non-dipping blood pressure. How to cite this article: Miazgowski T, Taszarek A, Miazgowski B. Visceral fat, cardiometabolic risk factors, and nocturnal blood pressure fall in young adults with primary hypertension.

show abstract

Reference standards for body fat measures using GE dual energy x-ray absorptiometry in Caucasian adults

Cited by 103 publications

References 32 publications

Body composition and physical fitness in women with bulimia nervosa or binge‐eating disorder

Body composition and physical fitness in women with bulimia nervosa or binge‐eating disorder

Persistence of a Posaconazole‐Mediated Drug‐Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety

Visceral fat, cardiometabolic risk factors, and nocturnal blood pressure fall in young adults with primary hypertension

Contact Info

Product

Resources

About