Refinement of the crystal structure of propionaldehyde 2,4-dinitrophenylhydrazone, C9H10N4O4

Abstract

Source of material 2,4-dinitrophenylhydrazine (1 mmol, 0.198 g) was dissolved in anhydrous ethanol (10 ml), H 2 SO 4 (98 %, 0.5 ml) was added to this, the mixture was stirred for several minutes at 351 K, propionaldehyde (1 mmol, 0.058 g) in ethanol (5 ml) was added dropwise and the mixture was stirred at refluxing temperature for 5 h. The product was separated and recrystallized in dichloromethane, red single crystals were obtained after 3 d. Discussion2,4-Dinitrophenylhydrazine is a reagent which is widely used for the condensation with aldehydes and ketones. Several phenylhydrazone derivatives have been shown to be potentially DNAdamaging and are mutagenic agents [1]. As part of our interest in the study of the coordination chemistry of Schiff base, we have synthesized the title compound and report its refined crystal structure. Due to the modern technique, more accurate data of the title compound firstly published in [2] are presented. In the title crystal structure, the molecule has a dihedral angle of 16.8 (2)