“…In a study by Cameli et al . [ 43 ], there was a strong association between LASr and cardiovascular events after adjustments, and both LA emptying fraction and LASr were superior and incremental to LAVI, suggesting that impaired reservoir function (LASr) may be a more sensitive indicator of left atrial remodeling [ 44 , 45 ]. Studies have shown an association between reduced LASr and contractile function, as well as paroxysmal AF that precedes LA enlargement [ 46 , 47 ].…”