Reflex Seizures as Initial Manifestations of Systemic Lupus Erythematosus in Childhood

Brinciotti, M.; Ferrucci, Giovanna; Trasatti, G.; Priori, Roberta; Squilloni, Elisabetta; Valesini, Guido

doi:10.1177/096120339300200118

Cited by 8 publications

(3 citation statements)

References 6 publications

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“…[14-16] Seizures can occur at any time during the course of SLE and all kinds of seizures may be seen in these patients (including generalized tonic-clonic, simple focal, and complex partial seizures). They may occur in isolation or along with the other neurological manifestations.…”

Section: Discussionmentioning

confidence: 99%

Neuropsychiatric manifestations of systemic lupus erythematosus: Iranian experience

Borhani‐Haghighi

Haza

2010

Ann Indian Acad Neurol

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Aims:To evaluate the prevalence and characteristics of different neurological and psychiatric presentations in patients admitted to hospital with systemic lupus erythematosus (SLE).Materials and Methods:In this retrospective hospital-based study, we examined the medical records of patients with SLE who were referred to the hospitals affiliated to Shiraz University of Medical Sciences from 1995 to 2005. All patients of SLE who had clinical neurological or psychiatric features were included in this study. The patients´ demographic data, findings on general examination, neuropsychiatric manifestations, and the results of laboratory investigations and imaging studies were recorded. Clinical manifestations were classified according to the American College of Rheumatology (ACR) case definitions.Results:Of the 407 study patients, 11.3% had neuropsychiatric complications. The most frequent findings were seizure (63%), headache (60%), and decreased level of consciousness (50%). Cerebrovascular disease (28.3%), seizure disorder (26.5%), and acute confusional state (19.6%) were the most prevalent syndromes.Conclusion:The prevalence and nature of different neurological presentations of SLE in Iranian patients has some similarities to that seen in other populations, as well as some differences. Ethnic and environmental factors may contribute to these differences.

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Section: Discussionmentioning

confidence: 99%

Neuropsychiatric manifestations of systemic lupus erythematosus: Iranian experience

Borhani‐Haghighi

Haza

2010

Ann Indian Acad Neurol

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“…All kinds of seizures (generalized, tonic-clonic, etc.) can take place any time during SLE either in isolation or association with other neurological conditions [28,29]. Most of our patients experienced seizures of focal onset in nature.…”

Section: Discussionmentioning

confidence: 77%

Pattern and prevalence of neuropsychiatric lupus: a retrospective study from a tertiary level hospital in Bangladesh

Hossain

Hawlader

Mitra

et al. 2021

Egypt J Neurol Psychiatry Neurosurg

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Background Neuropsychiatric systemic lupus erythematosus (NPSLE) is well known for its varying presentations and poor outcomes, but little is evident about its distribution and characteristics among the Bangladeshi population. This study aimed to assess the pattern and prevalence of neuropsychiatric symptoms in female systemic lupus erythematosus (SLE) patients of Bangladesh. A retrospective study was conducted at a tertiary care hospital in Dhaka, Bangladesh, between January and December 2018. One hundred female SLE patients were included in the study purposively. Data were collected on sociodemographic and clinical characteristics of diagnosed SLE cases visiting the SLE clinic and indoor medicine department. Neuropsychiatric (NP) syndromes were defined according to the widely accepted American College of Rheumatology (ACR) nomenclature and case definitions. Results A total of 244 NP events were identified in fifty-five patients. Headache was the most frequent symptom (55%), followed by cognitive dysfunction (50%), anxiety (49%), psychosis (43%), seizure (23%), depression (17%), and cerebrovascular disease (ischemic type, 7%). The NP manifestations were more prevalent among urban residents (58.2%), younger patients (41.8%), and patients with graduate-level education (34.5%). Besides, young age at diagnosis (p = 0.038), Raynaud’s phenomenon (p = 0.015), other organ involvement (p < 0.001), and time of NPSLE development (p < 0.001) were found to be significantly associated with the development of these manifestations. Conclusion NP damage is prevalent among Bangladeshi female SLE patients (55%) with headache and cognitive dysfunction being the most common symptoms. Routine screening for neuropsychiatric symptoms among suspected SLE cases and further evaluation with a larger population are warranted.

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“…Central nervous system involvement is reported in some cases, including seizures, psychosis, organic brain syndrome, aseptic meningitis and cognitive dysfunction. [2][3][4][5][6][7][8] A review of the literature was performed, and the presenting neurological features and therapies are summarized in Table 1.…”

Section: Partial Epilepsy As An Initial Manifestation In Bullous Systemic Lupus Erythematosusmentioning

confidence: 99%

Partial epilepsy as an initial manifestation in bullous systemic lupus erythematosus

Pan

Tang

Zhu

et al. 2011

Lupus

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Reflex Seizures as Initial Manifestations of Systemic Lupus Erythematosus in Childhood

Cited by 8 publications

References 6 publications

Neuropsychiatric manifestations of systemic lupus erythematosus: Iranian experience

Neuropsychiatric manifestations of systemic lupus erythematosus: Iranian experience

Pattern and prevalence of neuropsychiatric lupus: a retrospective study from a tertiary level hospital in Bangladesh

Partial epilepsy as an initial manifestation in bullous systemic lupus erythematosus

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