Reflux Gastritis Syndrome

Meshkinpour, Hooshang; Wittles, Joel

doi:10.1159/000171169

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Duodenogastric Reflux: the State Of The Art1

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1990

2012

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Cited by 2 publications

(1 citation statement)

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“…The occurrence of pathological DGR has been most commonly recognized in adult populations following gastric surgery such as antrectomy and Billroth II reconstruction (5). The postsurgical syndrome characterized by nausea, frequent bilious vomiting, and continuous burning, midepigastric pain unresponsive to medical therapies, termed "alkaline reflux gastritis," is thought to be due to DGR (14). Experimental observations in both the dog and man have demonstrated, however, that episodes of pathological DGR do occur without previous gastric surgery.…”

Section: Duodenogastric Reflux: the State Of The Artmentioning

confidence: 99%

Duodenogastric Reflux

1990

J. pediatr. gastroenterol. nutr.

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Section: Duodenogastric Reflux: the State Of The Artmentioning

confidence: 99%

Duodenogastric Reflux

1990

J. pediatr. gastroenterol. nutr.

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Respiratory Pathogens Adopt a Chronic Lifestyle in Response to Bile

et al. 2012

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Chronic respiratory infections are a major cause of morbidity and mortality, most particularly in Cystic Fibrosis (CF) patients. The recent finding that gastro-esophageal reflux (GER) frequently occurs in CF patients led us to investigate the impact of bile on the behaviour of Pseudomonas aeruginosa and other CF-associated respiratory pathogens. Bile increased biofilm formation, Type Six Secretion, and quorum sensing in P. aeruginosa, all of which are associated with the switch from acute to persistent infection. Furthermore, bile negatively influenced Type Three Secretion and swarming motility in P. aeruginosa, phenotypes associated with acute infection. Bile also modulated biofilm formation in a range of other CF-associated respiratory pathogens, including Burkholderia cepacia and Staphylococcus aureus. Therefore, our results suggest that GER-derived bile may be a host determinant contributing to chronic respiratory infection.

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Reflux Gastritis Syndrome

Cited by 2 publications

References 30 publications

Duodenogastric Reflux

Duodenogastric Reflux

Respiratory Pathogens Adopt a Chronic Lifestyle in Response to Bile

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