Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Kam, Joseph Wai Keung; Gauvin, Mathieu; Adiguzel, Eser; Bashour, Mounir; Kalevar, Ananda; Cohen, Mark E.

doi:10.1186/s12886-020-01481-2

Cited by 11 publications

(7 citation statements)

References 50 publications

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“…22,29,30 In high myopes evaluated 2 years after undergoing LASIK, UDVA was at least 20/20 in 50.9% of eyes, at least 20/25 in 80.7% of eyes, and at least 20/40 in 95.6% of eyes. 21 Myopic regression rates in our patients with hypermobile EDS were comparable or possibly even more favorable than those seen in the general population. Myopic regression can be caused by biomechanical changes in the cornea, epithelial hyperplasia, stromal remodeling, errors in treatment (imprecise preoperative refraction or not enough laser energy), development of cataract, or axial elongation.…”

Section: Discussionsupporting

confidence: 70%

“…22,29,30 In high myopes evaluated 2 years after undergoing LASIK, UDVA was at least 20/20 in 50.9% of eyes, at least 20/25 in 80.7% of eyes, and at least 20/40 in 95.6% of eyes. 21…”

Section: Discussionmentioning

confidence: 99%

“…20 High myopes were also generally happy with the procedure, with 90.5% reporting quality of vision significantly improved compared to prior. 21 An amalgam of multiple studies representing 9726 patients reported that 46.4% were "very satisfied" after surgery and only 1.2% were dissatisfied. 22 Dry eye seems to have affected our study population more frequently than the average person undergoing LASIK.…”

Section: Discussionmentioning

confidence: 99%

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Outcomes and Complications in Patients With Hypermobile Ehlers–Danlos Syndrome Who Have Undergone Laser In Situ Keratomileusis Surgery

Gauthier¹,

Bower²,

Singman³

2022

Cornea

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The purpose of this study was to determine the safety and outcomes of myopic laser in situ keratomileusis (LASIK) in patients who were secondarily diagnosed with hypermobile Ehlers-Danlos syndrome (EDS). Methods:We conducted a case series study on patients with hypermobile EDS who underwent myopic LASIK surgery. Visual acuity, manifest refraction, a full dilated eye examination, biometry measurements, and Scheimpflug imaging were performed in the Wilmer outpatient clinic.Results: There were 24 eyes of 12 patients included in this study.All participants were White women with a mean age of 46.58 years (SD 8.91 years). Participants were seen at an average of 13.83 years (SD 4.3 years, range 6-21 years) after undergoing LASIK. None of the patients in the series had a diagnosis of hypermobile EDS before LASIK surgery. Overall, 92% of patients were happy they got LASIK. The uncorrected distance visual acuity was 20/20 or better in 68% of eyes, and the best-corrected visual acuity was 20/20 or better in 92% of eyes. Manifest refraction was within 1 diopter of plano in 79% of patients. Dry eye symptoms were present in 83% of patients, and 46% of eyes had either punctate epithelial erosions or decreased tear break-up time. One of the 12 patients developed corneal ectasia in both eyes.Conclusions: Patients with hypermobile EDS are generally satisfied with myopic LASIK correction, with good visual acuity outcomes and low rates of myopic regression. However, the risk of corneal ectasia may prevent laser vision correction from being a viable treatment option in these patients. Further studies are needed to make a definitive recommendation.

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Section: Discussionsupporting

confidence: 70%

“…22,29,30 In high myopes evaluated 2 years after undergoing LASIK, UDVA was at least 20/20 in 50.9% of eyes, at least 20/25 in 80.7% of eyes, and at least 20/40 in 95.6% of eyes. 21…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Outcomes and Complications in Patients With Hypermobile Ehlers–Danlos Syndrome Who Have Undergone Laser In Situ Keratomileusis Surgery

Gauthier¹,

Bower²,

Singman³

2022

Cornea

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“…With regard to the high myopia group in the current study (which we defined as a preoperative SE of −10.0 D or higher), the LASIK efficacy was poorer than for the other two groups, as only 26.5% of these eyes achieved a UCVA of ≥20/20, although 91.2% achieved a UCVA of ≥20/40. In previous reports on cases with more severe myopia, higher ablation was followed by more wound healing and myopic regression, and surgeons seemed to perform undercorrection when faced with limits imposed by corneal thickness [ 28 , 32 , 33 ].…”

Section: Discussionmentioning

confidence: 99%

Three-Year Follow-Up of Laser In Situ Keratomileusis Treatments for Myopia: Multi-Center Cohort Study in Korean Population

Kim

Lee

Joo

et al. 2021

JPM

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This multi-center cohort study included 3401 myopic laser in situ keratomileusis (LASIK) procedures conducted in 1756 myopia patients between 2002 and 2005. Pre- and postoperative uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and manifest refraction spherical equivalent (SE) were recorded. Factors predicting low postoperative efficacy (defined as a postoperative UCVA < 0.5) were identified using univariate and multivariate logistic regression analysis. Compared with 1 month postoperatively, logMAR UCVA at 3 months postoperatively was significantly decreased (p = 0.002) and that at 2 and 3 years was significantly increased (p < 0.001). LogMAR BCVA at 2 years postoperatively was significantly decreased compared with 1 month postoperatively (p = 0.008). Over the 3-year postoperative period, overall refractive predictability within ±1.00 D and ±0.50 D ranged from 69.0% to 86.2% and from 43.3% to 67.8%, respectively. This also decreased from 1 month to 6 months postoperatively (p < 0.005). Multivariate logistic regression analysis using generalized estimating equations, revealed that higher preoperative SE (odds ratio [OR], 2.58 and 7.23; p < 0.001) and lower preoperative BCVA (OR, 2.44; p = 0.003) were predictive of a low postoperative efficacy. In summary, myopic LASIK can be effective and safe with a high refractive predictability in a Korean population, but myopic regression occurs over time. Higher preoperative SE and lower preoperative BCVA are predictive of a low postoperative efficacy.

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“…Comparatively, in one study by Wallerstein et al, they operated on 114 eyes from 78 cases who experienced LASIK at the Canadian Institute of Refractive Surgery. After 24 months post-surgery, the scatterplot of the tried against actual refractive adjustment showed an expected technique with 51.7%, 71.9%, 84.2%, and 93.8% existing in ± 0.25 D, ± 0.50 D, ± 0.75 D, and ± 1.00 D, of SEQ aim [13]. Kanellopoulos and Asimellis operated on 160 eyes with high myopia ⩾ − 6.00 D, with postoperative average spherical equivalents at − 0.37, − 0.43, and − 0.25 D for the 3, 6, and 12 months, which was also predictable [14].…”

Section: Discussionmentioning

confidence: 92%

Pentacam versus anterior segment OCT in measuring intended versus achieved ablation depth post-myopic LASIK correction

Khalil

Abd-Elhafiz

Ibrahim

2022

Beni-Suef Univ J Basic Appl Sci

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Background Accurate quantitative measurements of central corneal thickness (CCT) provide valuable, clinical information for preoperative assessment, surgical planning, and follow-up in myopic patients who have undergone LASIK correction. Typically, an ultrasound is used to measure such parameters. However, noncontact devices such as the Visante anterior segment optical coherence tomographer [AS-optical coherence tomography (OCT)] and Pentacam are becoming more popular to measure ocular parameters. It is important to assess the level of similarity between these two optical devices to compare between the intended and achieved ablation depth after LASIK procedures in cases of myopia and myopic astigmatism. Methods This cross-sectional, prospective study included 80 eyes of 40 patients attending Beni-Suef University Hospital between November 2018 and November 2019. All patients underwent LASIK surgery for the correction of myopia with or without myopic astigmatism with spherical equivalent ranging from − 1.5 to − 12 diopters. Results No statistically significant difference was observed between the intended ablation depth and the clinically measured ablation depth calculated by Pentacam and AS-OCT 3 months after surgery (P > 0.05). Conclusion When planning corneal refraction surgery, ablation depth readouts calculated by the computer software of the excimer laser used in this study are reliable. Both Pentacam and AS-OCT are accurate, sensitive, and specific in measuring the CCT and calculating ablation depth. Pentacam provides slightly higher accuracy and sensitivity compared with AS-OCT. LASIK is a safe, predictable, and effective procedure in the treatment of simple myopia and myopic astigmatism.

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Refractive, visual, and subjective quality of vision outcomes for very high myopia LASIK from − 10.00 to − 13.50 diopters

Cited by 11 publications

References 50 publications

Outcomes and Complications in Patients With Hypermobile Ehlers–Danlos Syndrome Who Have Undergone Laser In Situ Keratomileusis Surgery

Outcomes and Complications in Patients With Hypermobile Ehlers–Danlos Syndrome Who Have Undergone Laser In Situ Keratomileusis Surgery

Three-Year Follow-Up of Laser In Situ Keratomileusis Treatments for Myopia: Multi-Center Cohort Study in Korean Population

Pentacam versus anterior segment OCT in measuring intended versus achieved ablation depth post-myopic LASIK correction

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