Regenerative Surgery &amp; Intra-Operative Protocols Utilizing Bone Marrow Aspirate Concentrate in Microsurgical &amp; Limb Reconstruction

Miller, Timothy J.; Rodriguez-Collazo, Edgardo; Frania, Stephen J.; Thioné, Alessandro

doi:10.29337/ijops.29

Cited by 2 publications

(2 citation statements)

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“…Bone marrow aspirate and plateletrich plasma are utilized adjunctively to promote active regeneration into the nerve allograft of the distal transected nerve. 14 It should be noted that a reset neurectomy or reset neurotomy (depending if there is a nerve resection or nerve division without segmental resection) has been performed only in sensory nerve injuries. Because there was no identifiable neuroma or injury, no nerve segment was resected.…”

Section: Discussionmentioning

confidence: 99%

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The Reset Neurotomy within a Nonidentifiable Zone of Injury after Trauma

Schnack,

Rodriguez-Collazo,

Oexeman

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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Summary: Recent reconstructive approaches to peripheral nerve surgery have been directed toward active approaches; one such approach is nerve grafting the injured nerve segment. Addressing a nerve injury proximal to the zone of injury has demonstrated reproducible results in preventing symptomatic neuroma formation. A 53-year-old woman with a history of an ankle fracture presented with neuritic symptoms that interfered with her activities of daily living. Her intractable pain was significantly but temporarily relieved with in-office nerve blocks to the superficial peroneal nerve and sural nerve. There were no identifiable zones of injury in the nerve conduction study. Orthopedic etiology was ruled out. Nerve allografts, each 3 cm in length, were utilized with conduits and placed at the location proximal to the zone of maximum tenderness. Once the neurotomy was performed, the nerve allografts and conduits were coapted to each nerve. The patient’s intractable neuritic pain was relieved even 15 months postoperatively. The visual analog scale went from eight of 10 preoperatively to two of 10 postoperatively. Additional nerve conduction studies were not needed, and the patient returned to daily activities once the skin incisions healed. The reset neurotomy is an option for the microsurgical surgeon to have for patients with a nonidentifiable zone of injury or no identifiable neuroma but presents with intractable nerve pain relieved by local anesthetic nerve blocks.

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Section: Discussionmentioning

confidence: 99%

“…Bone marrow aspirate and platelet-rich plasma are utilized adjunctively to promote active regeneration into the nerve allograft of the distal transected nerve. 14 …”

Section: Discussionmentioning

confidence: 99%