Regional variation in the development of neonatal hyperbilirubinemia and relation with sunshine duration in Japan: an ecological study

Kuniyoshi, Yasutaka; Tokutake, Haruka; Takahashi, Natsuki; Kamura, Azusa; Yasuda, Sumie; Tashiro, M.

doi:10.1080/14767058.2021.1873270

Cited by 4 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The emission of blue-green light by sunshine has the potential to prevent hyperbilirubinemia by promoting the conversion of bilirubin to its water-soluble isomers, thereby facilitating its excretion. The inverse correlation observed between the duration of sunshine and the incidence of neonatal hyperbilirubinemia at the prefectural level could potentially be attributed to the impact of sunlight exposure penetrating the living environments of infants (Kuniyoshi et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

Effect of Seasonal Variation on the Bilirubin Content and Hematological Indices among Neonates in Southern Gaza, Palestine

El-Habiby¹,

Mustafa²,

Mohieldein³

2023

GJHS

View full text Add to dashboard Cite

BACKGROUND & OBJECTIVES: Premature newborns’ bilirubin conjugation and excretion mechanisms are undeveloped. Seasonal changes and other variables affect the severity of newborns’ physiological jaundice. This study examined blood indices, bilirubin levels, and birth season in neonates in the southern Gaza Strip of Palestine. METHODS: A cross-sectional study of 366 neonates aged one to 14 days was conducted in Medical Nasser Complex-Southern Gaza, Palestine.The newborns were divided into four groups based on season of birth: spring (n=72), winter (n=96), autumn (n=103) and summer (n=95). Blood samples were collected in plain vacutainers for assaying bilirubin profile and complete blood count. Bilirubin and complete blood count were assayed by commercial kits. SPSS software was used for data analysis. RESULTS: Indirect and total bilirubin showed significant seasonal variations, whereas direct did not. Spring and winter have increased indirect and total bilirubin. Seasonal hemoglobin levels varied significantly. Red blood cells, hemoglobin, and hematocrit positively correlated with total and indirect bilirubins. CONCLUSION: Spring and winter births exhibited higher indirect and total bilirubin in the first two weeks. The birth season appears to affect newborn jaundice. Short sunshine duration may increase neonatal hyperbilirubinemia risk.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Seasonal Variation on the Bilirubin Content and Hematological Indices among Neonates in Southern Gaza, Palestine

El-Habiby¹,

Mustafa²,

Mohieldein³

2023

GJHS

View full text Add to dashboard Cite

show abstract

“…The NDB includes the diagnoses provided by physicians and can be used to describe disease trends and patterns. In Japan, several studies have been conducted on a national level to describe specific diseases in children, such as the number of children diagnosed with cerebral palsy [11] and the number of newborns undergoing phototherapy for neonatal hyperbilirubinemia [12]. However, to the authors' knowledge, there are no Japanese studies that describe the frequency of diseases across a wide range of diseases in children and adolescents.…”

Section: Introductionmentioning

confidence: 99%

Disease Trends in Children and Adolescents in Japan: A Retrospective Observational Study Using the Nationwide Claims Data for 2012–2016

Suto,

Takehara,

Morisaki

et al. 2024

Children

View full text Add to dashboard Cite

This study aimed to clarify diseases that occur more frequently by age and identify the peaks and trends of each disease from infancy to adolescence for early detection and treatment. This retrospective observational study was conducted using Japan’s National Database of Health Insurance Claims Specific Health Checkups from January 2012 to December 2016. Using peak ages and trends in the number of patients, we grouped diseases by the International Classification of Diseases chapters. Although diseases that peaked during infancy were the most common (10 disease chapters), other diseases peaked at school-going age and adolescence. Diseases in four chapters peaked during adolescence and continued to increase toward the age of 18. These four chapters included mental, behavioral, and neurodevelopmental disorders; diseases of the nervous system; the genitourinary system; and pregnancy, childbirth, and the puerperium. Childhood-onset diseases can affect long-term health and healthcare needs, and timely screening and guidance based on disease trends can provide an effective intervention. To establish a child healthcare system that provides preventive support for children and adolescents’ physical, psychological, and social health, further research is needed to comprehensively understand the issues per age and developmental stage.

show abstract

“…Hyperbilirubinemia in newborns is most common now. [ 1 ] Phototherapy is generally the preferred treatment for severe neonatal hyperbilirubinemia. [ 2 ] Hyperbilirubinemia mainly results in an imbalance between the production and elimination of bilirubin in newborns.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and association of early onset severe hyperbilirubinemia in newborn in the East China region: Retrospective medical record analyses

Gao,

Zhao,

Chen

et al. 2023

Medicine

View full text Add to dashboard Cite

Research on the prevalence and association of hyperbilirubinemia is controversial because of different cultures, demographics, and clinical conditions. The etiology of hyperbilirubinemia is affected by the environment and other factors in the newborn. The World Health Organization recommended a 1-day hospital stay after uncomplicated delivery, jaundice assessment before discharge, and screening on 3rd and 7th days after birth for hyperbilirubinemia. However, the implementation of these recommendations is difficult in China. The objective of this study was to evaluate the prevalence and association of early onset severe hyperbilirubinemia in newborns in East China. Retrospective medical record analyses for 250 cesarean sections or vaginal deliveries, ≥2 kg body weight, and negative for Hepatitis B surface antigen by birth newborns were performed. A biochemical analyzer, quantitative assay, and quantitative polymerase chain reaction were used to evaluate total serum bilirubin, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and gene variant phenotyping, respectively. A total in 33 (13%) newborns were reported with early onset severe hyperbilirubinemia (according to the American Academy of Pediatrics, total serum bilirubin ≥ 342 μmol/L within 6 hours of birth). All newborns with severe hyperbilirubinemia were hospitalized and underwent phototherapy. The mothers of all newborns had a gestational age ≥ 35 weeks. Hospitalization included artificial feeding, and breastfeeding was rare (P < .0001). ABO incompatibility (“O” blood type for mother and either “A” or “AB” or “B” blood type for newborn, P = .0411), G6PD deficiency (G6PD/6-phosphogluconate dehydrogenase ≤ 1.0 in quantitative assay, P = .0422), Rh incompatibility (the mother’s blood type was Rh negative and newborn blood type was Rh positive, P = .0416), fewer genotype rs4149056 frequencies (P = .0452), higher genotype rs2306283 frequencies (P = .0461), and higher genotype rs1805173 frequencies (P = .0471) were independent parameter for early onset severe hyperbilirubinemia of newborns. The prevalence of early onset severe hyperbilirubinemia in Chinese newborns is 13% in the East China region. Blood incompatibility, G6PD deficiency, fewer genotype rs4149056 frequencies, higher genotype rs2306283 frequencies, and higher genotype rs1805173 frequencies were independent predictors of early onset severe hyperbilirubinemia among newborns in the East China region (Level of Evidence: IV; Technical Efficacy: Stage 5).

show abstract

Regional variation in the development of neonatal hyperbilirubinemia and relation with sunshine duration in Japan: an ecological study

Cited by 4 publications

References 20 publications

Effect of Seasonal Variation on the Bilirubin Content and Hematological Indices among Neonates in Southern Gaza, Palestine

Effect of Seasonal Variation on the Bilirubin Content and Hematological Indices among Neonates in Southern Gaza, Palestine

Disease Trends in Children and Adolescents in Japan: A Retrospective Observational Study Using the Nationwide Claims Data for 2012–2016

Prevalence and association of early onset severe hyperbilirubinemia in newborn in the East China region: Retrospective medical record analyses

Contact Info

Product

Resources

About