Regional variations in the concentrations of ketone bodies in cirrhosis and hepatic encephalopathy: a study in patients with TIPSS

Abstract

There are significant variations in the regional concentrations of the ketone bodies in encephalopathy.

Free fatty acid as a marker of energy malnutrition in liver cirrhosis

“…In a fasting state, ketone body is also one of energy substrates for total body tissue, especially in the brain. 38 Previous studies demonstrated that the concentration of ketone body is elevated in cirrhotic patients after starvation, in a similar manner to FFA. 26,27 In this study, there was a correlation between npRQ and ketone body in a fasting state (Table 3), but ketone body did not correlate with the Child-Pugh classification (Table 1).…”

“…Ketone body is synthesized mainly in the liver by β‐oxidation of FFA derived from the adipose tissue. In a fasting state, ketone body is also one of energy substrates for total body tissue, especially in the brain . Previous studies demonstrated that the concentration of ketone body is elevated in cirrhotic patients after starvation, in a similar manner to FFA .…”