Regulated peristalsis into the acidic region of the Drosophila larval midgut is controlled by a novel component of the Autonomic Nervous System

Abstract

Number of figures and tables: 2 figures and 3 tables Contents of supplemental material: 3 tables, 2 movies

All for one and one for all: Regionalization of the Drosophila intestine

“…This suggests that the local innervation of midgut extremities could regulate food transit in and out of the midgut. However, peristalsis appears so far to be the only mechanism regulating transit inside the midgut, which could be regulated by entero-endocrine cells enriched in the midgut domains devoid of neurons (Buchon et al, 2013b;Cognigni et al, 2011;LaJeunesse et al, 2009). EEs secrete numerous neuropeptides that are highly patterned along the gut length but their physiological functions and mode of action remain largely unknown (Beehler-Evans and Micchelli, 2015;Song et al, 2014;Veenstra, 2009).…”