2017
DOI: 10.1002/cbic.201700545
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Regulating DNA Self‐assembly by DNA–Surface Interactions

Abstract: DNA self-assembly provides a powerful approach for preparation of nanostructures. It is often studied in bulk solution and involves only DNA-DNA interactions. When confined to surfaces, DNA-surface interactions become an additional, important factor to DNA self-assembly. However, the way in which DNA-surface interactions influence DNA self-assembly is not well studied. In this study, we showed that weak DNA-DNA interactions could be stabilized by DNA-surface interactions to allow large DNA nanostructures to fo… Show more

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Cited by 32 publications
(47 citation statements)
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“…The TET easily collapsed on a mica surface due to its open triangular facets and showed an average height of 2.5 nm, which was consistent with that reported in the literature . In addition to the regular thermal annealing process, the Cyst 2+ ‐containing buffer was also compatible with an isothermal annealing strategy for DNA assembly by supplementing with 5 % ( v / v ) formamide (termed as TAF/Cyst) . The gel image in Figure S7 provides evidence of the isothermal formation of TET in high yield by employing the slightly altered buffer recipe.…”
Section: Figurementioning
confidence: 99%
“…The TET easily collapsed on a mica surface due to its open triangular facets and showed an average height of 2.5 nm, which was consistent with that reported in the literature . In addition to the regular thermal annealing process, the Cyst 2+ ‐containing buffer was also compatible with an isothermal annealing strategy for DNA assembly by supplementing with 5 % ( v / v ) formamide (termed as TAF/Cyst) . The gel image in Figure S7 provides evidence of the isothermal formation of TET in high yield by employing the slightly altered buffer recipe.…”
Section: Figurementioning
confidence: 99%
“…Along with the effects of pH and temperature, the effect of ions/ionic strength on the self-assembly of proteins [129,130], peptides [131], DNA [132], and RNA [133] molecules have been reported.…”
Section: External Stimulations Towards Biomolecular Self-assemblymentioning
confidence: 99%
“…DNA nanostructure can attach to hydrophilic surfaces, especially positively charged ones, via van der Waals forces or electrostatic interaction . Current use of DNA nanostructure in patterning generally falls into one of three general approaches: deposition, etching, and imprinting.…”
Section: Dna‐based Nanofabricationmentioning
confidence: 99%