Relating pressure tuned coupled column ensembles with the solvation parameter model for tunable selectivity in gas chromatography

Pressure Tuning of First Dimension Columns in Comprehensive Two-Dimensional Gas Chromatography

“…At P j 60 psi, the contribution of the IL column is estimated to increase by about 70% of the separation (φ IL = 0.681). This observation is similar to that of previous work where the impacts of decompression on individual column characteristics were reported …”

“…This observation is similar to that of previous work where the impacts of decompression on individual column characteristics were reported. 20 Alternatively, the 2D chromatograms in Figure 2 show changes in peak position arising from changing P i at fixed P j = 30 psi. While the variation of P j significantly changed residence time of both 1 D 1 and 1 D 2 columns (Figure 1), P i variation S1.…”

“…18,19 A further account of selectivity dependence by using PT was reported recently. 20 It may be a coincidence that recent developments in multidimensional gas chromatography (MDGC) and comprehensive two-dimensional gas chromatography (GC × GC) have reduced the popularity of pressure tuning in GC; the goals of PT GC, MDGC, and GC × GC are all focused on improved separation of mixtures. GC × GC techniques have attracted attention in recent years due to factors such as its high resolution, high peak capacity in a given time, improved detectability, and structured retentions.…”

“…This essentially represents the knowledge base established to the end of 2005, when PT apparently came to a halt. Recently, the mathematical background to coupled-column separation based on thermodynamic interactions was reported. , A further account of selectivity dependence by using PT was reported recently . It may be a coincidence that recent developments in multidimensional gas chromatography (MDGC) and comprehensive two-dimensional gas chromatography (GC × GC) have reduced the popularity of pressure tuning in GC; the goals of PT GC, MDGC, and GC × GC are all focused on improved separation of mixtures.…”

Multi-column trajectory to advanced methods in comprehensive two-dimensional gas chromatography

“…Unsaturated FAME retain almost 5 minutes more when the φwax10 value increased by 0.13, and the boxed FAME group elutes over a range of 1.7 min, at pj = 26, compared with 2.7 min, at pj = 30 psiso unsaturated FAME elute relatively later. Moreover, the resultant apparent adjustment of ensemble property may lead to peaks swapping their positions on 1 D, according to the analytes and stationary phase-specific interactions, which could be classified by the LSER method [18]. Modification of peak positions in 2D space by PT, depends on two interrelated propositions; one is the direct effect on void time ( 2 tm) and another is the variation of elution temperature (Te) to the 2 D column, since as solute retention is delayed on 1 D, Te will increase and 2 tR will decrease.…”