Relation between coronary atherosclerotic plaques and traditional risk factors in people with no history of cardiovascular disease undergoing multi-detector computed coronary angiography

Abstract

A direct relation between the prevalence of CAP, number of risk factors and the related 10-year risk of CVE was found. 18% of subjects without risk factors had CAP. In these individuals CTCA may help in further optimising the risk reduction strategies on an individual basis.

Personality traits, cardiac risk factors, and their association with presence and severity of coronary artery plaque in people with no history of cardiovascular disease

“…A more detailed description of the procedure is provided by Faletra et al 4 Image datasets were reconstructed immediately after the scan. Two experienced observers with knowledge of the individual's clinical history and indications for patient referral evaluated the CTCA in a joint reading manner.…”

“…Indeed, a significant number of cardiovascular events occur either in the absence of known risk factors or in the presence of moderate risk when an aggressive treatment strategy is not indicated. Faletra et al 4 show that 18% of patients who were expected to be at low risk of cardiovascular events, due to absence of CRFs, showed evidence of CAP. Conversely, 12% of patients who had three or more risk factors showed no CAP presence.…”

“…Conversely, 12% of patients who had three or more risk factors showed no CAP presence. 4 Moreover, large population studies aimed at investigating the frequency of exposure to major conventional coronary artery disease (CAD) risk factors have shown that 13 and 17% of those with fatal 5 or nonfatal 6 CAD events, respectively, had not been exposed to major risk factors. These data leave room for the hypothesis that other risk factors, such as lifestyle factors, genetic predisposition, or psychological factors, 7 play a potential role in CAP presence, severity, and development.…”

Coronary Calcium Scoring and Modifiable Coronary Risk Factors

“…[5] Eighteen percentage of subjects without coronary risk factors have been found to have coronary plaque. [6] No association has been found between the degree of stenosis and plaque composition or vulnerability. [7] Thus, all of the coronary risk factors included in our study do not essentially state the plaque burden.…”

Trend of lipid ratios associated with well known risk factors of coronary artery disease in different age: A population based study of 31,999 healthy individuals

“…Ascertainment of the variations among populations concerning the pattern of CAD conventional [2][3][4][5][6][7][8][9][10][11][12][13][14][15] and novel [13,16] risk factors illuminates the puzzling aspects of the disease.…”