Relation between myocardial oxygen consumption and myocardial blood volume: A study using myocardial contrast echocardiography

Le, D. Elizabeth; Bin, Jian Ping; Coggins, Matthew; Wei, Kevin; Lindner, Jonathan R.; Kaul, Sanjiv

doi:10.1067/mje.2002.121275

Cited by 52 publications

(52 citation statements)

References 19 publications

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“…12 At the level of the microvasculature, only 75% of the increase in CBF was associated with increases in myocardial blood volume, whereas the remainder occurred from increases in red blood cell velocity. .…”

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confidence: 99%

Perfusion Versus Function: The Ischemic Cascade in Demand Ischemia

et al. 2002

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Background-We hypothesized that during demand ischemia, abnormal perfusion will precede abnormal function, the spatial extent of perfusion abnormality will be greater than that of functional abnormality, and the spatiotemporal disparity between abnormal perfusion and abnormal function will be more marked in the presence of single-vessel stenosis (SVS) versus multivessel stenosis (MVS). Methods and Results-Nine dogs each underwent either SVS or MVS placement. These noncritical stenoses were classified as mild, moderate, or severe on the basis of the transstenotic pressure gradient (10 to 14, 15 to 20, or Ͼ20 mm Hg). Dobutamine was infused starting at 10 and reaching 40 g/kg Ϫ1 · min

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confidence: 99%

Perfusion Versus Function: The Ischemic Cascade in Demand Ischemia

et al. 2002

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“…9 The total blood carrying capacity of the abnormal dilated vessels of the malignant tumors and of the vessels of vascular tumors (e.g., hemangioma) is probable to be in excess of that of the adjacent myocardium. Stromal tumors have lower vascularization and thrombi are avascular.…”

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confidence: 99%

Myocardial contrast echocardiography in the diagnosis of a left ventricular hemangioma

Papadopoulos¹,

Makrides

2016

Ital J Med

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Myocardial perfusion contrast echocardiography is an imaging tool for the assessment of myocardial microcirculation. It can also be used for the evaluation of the relative perfusion of a cardiac mass. Cardiac hemangiomas are rare tumors, accounting for only 2.8% of all benign primary cardiac tumors. We report a case of a 17-year-old man with a left ventricular hemangioma detected with transthoracic echocardiography. Myocardial perfusion contrast echocardiography was used to evaluate the vascularity of the cardiac mass. Using this technique malignant and hypervascular (e.g., hemangioma) tumors display persistence of contrast enhancement compared to the surrounding myocardium. The mass was successfully removed and the final report from pathology showed that the left ventricular mass was a hemangioma, a hypervascular tumor.

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“…In addition to the rapid filling seen with dobutamine, we also see an appreciable increase in myocardial opacification because dobutamine increases myocardial blood volume. 17,18 At low doses, dobutamine is a vasodilator, and at higher doses it recruits more capillaries to meet the increased myocardial oxygen needs. 18 Lack of increase in myocardial opacification also indicates the presence of CAD.…”

Section: Detection Of Coronary Artery Diseasementioning

confidence: 99%