Relation between renal resistive index and renal function in septic patients developing acute kidney injury 2

Abstract

Introduction:Acute kidney injury (AKI) is a common clinical problem encountered in critically ill patients, frequently in the setting of multiple organ failure, and is an independent risk factor for increase hospital stay and mortality risk. Renal resistive index (RRI) can be measured by renal Doppler ultrasound, RRI reflects changes in blood flow profile of the intrarenal arcuate or interlobar arteries. RRI=(peak systolic velocity−end diastolic velocity)/(peak systolic velocity) in order to detect the relation between renal resistive index and renal function in AKI septic patients received hemodialysis either transient (< 3 sessions) or permanent (> 3 sessions). 40 AKI septic patients received hemodialysis were subjected to renal duplex measurements on admission and after 48h and patients were followed till hospital discharge to detect the relation between RRI and renal functions. 27 patients (67.5%) with RRI (0.5 ± 0.1) had transient hemodialysis and 13 patient (32.5%) with RRI (0.9 ± 0.1) had permanent hemodialysis. There was a statistically significant positive correlation between RRI after 48 hours and serum creatinine level (p. < 0.05). Conclusion:We detected a statistically significant positive relationship between renal resistive index and renal functions.