Relationship among Egg Productivity, Steroid Hormones (Progesterone and Estradiol) and Ovary in Korean Native Ogol Chicken

Kang, Woojin; Yun, J. S.; Seo, D. S.; Ko, Yongmin

doi:10.5713/ajas.2001.922

Cited by 11 publications

(6 citation statements)

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“…egg production) and moulting progress of poultry. Kang et al (2001) reported that high egg production is associated with higher weights of ovary and follicles and higher progesterone confirmed the positive relationship of progesterone expression with egg production. The elevated levels of prolactin in birds play a negative role in reproductive performance.…”

Section: Introductionmentioning

confidence: 62%

Effect of zinc oxide, potassium iodide and withdrawal diet as alternative moulting methods on performance of commercial laying hens

Kazemifard

Ghasemi

Dirandeh

et al. 2020

Journal of Applied Animal Research

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Section: Introductionmentioning

confidence: 62%

Effect of zinc oxide, potassium iodide and withdrawal diet as alternative moulting methods on performance of commercial laying hens

Kazemifard

Ghasemi

Dirandeh

et al. 2020

Journal of Applied Animal Research

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“…(Kang et al, 2001), which is far less than that of the White Leghorn (>350) (Robert, 1996). Moreover, the average egg weight of KNOC is approximately 50 g from sexual maturity to 60 wk (Kang et al, 2001), which is lighter than that of the White Leghorn (>60 g) (Su and Silversides, 1996). These suggest that KNOC needs to be improved for egg productivity as a layer.…”

Section: Discussionmentioning

confidence: 87%

Association among Egg Productivity, Granulosa Layer IGF-I, and Ovarian IGF-I in Korean Native Ogol Chicken

Kang¹,

Seo²,

Ko³

2003

Asian Australas. J. Anim. Sci

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There exists considerable evidence that insulin-like growth factor-I (IGF-I) is involved in the regulation of ovulation rate and follicle development. IGF-I is believed to modulate the effects of gonadotropins on follicular growth and cell differentiation via paracrine and autocrine mechanisms. Therefore, this study was performed to relate the expression of IGF-I on ovaries and follicles with egg productivity at 60 wk. The egg productivity of 70 KNOC was recorded from 20 to 60 wk. Blood was taken every 10 wk and ovaries and follicles were taken at 60 wk. Serum IGF-I and IGF-I of ovaries and follicles were measured by radioimmunoassay. Based on egg production levels up to 60 wk and ovarian IGF-I expression at 60 wk, respectively. Chickens were divided into two groups, high and low. Egg production and serum IGF-I in the high IGF-I group were higher than those in the low group. Moreover, the IGF-I expression of follicles in the high ovarian IGF-I expression group was higher than that in the low group. These finding are consistent with the report that IGF-I indirectly regulates ovulation in chickens, suggesting that this regulation may play an important role in improved egg productivity.

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“…In our previous transcriptome database, we found circEML1 was differentially expressed in hens’ ovarian tissue at the ages of 15W, 20W, 30W and 68W, and the highest expression of circEML1 was presented in the ovary of 30W. It is well-known that hen’s ovary contained a large numerous of follicles with different sizes and strongly produced steroid hormones to maintain the ovulation processing during the peak laying period (30-40w), which indicated that the regulatory role of circEML1 might be associated with steroidogenesis[40, 41]. In recent years, circRNAs have been proven to drive as a sponge of miRNA to competitively bind miRNA and release the expression of downstream target genes, which participated in the modulation of reproductive mechanism in various mammals, including follicular GC proliferation, apoptosis and steroidogenesis, for instance, circEGFR increased E2 secretion and enhance ovarian GC proliferation by regulating miR-125a-3p and Fyn; ssc-circINHA-001 regulated follicular GC apoptosis via sponging miR-241-5p, miR-7144-3p and miR-9830-5p to enhance the expression of downstream gene INHBA; and the depletion of circLDLR could decrease estrogen secretion via regulating miR-1294 and CYP19A1 expression as a ceRNA network [42–44].…”

Section: Discussionmentioning

confidence: 99%

CircEML1 facilitates the steroid synthesis in follicular granulosa cells of chicken through sponging gga-miR-449a to release IGF2BP3 expression

et al. 2022

Preprint

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Non-coding RNAs (ncRNAs) induced competing endogenous RNAs (ceRNA) play crucial roles in various biological process by regulating target gene expression. However, the studies of ceRNA networks in the regulation of ovarian ovulation process of chicken remains deficient compared to that in mammals. In the present study, it was revealed that circEML1 was differential expressed in hen’s ovarian tissue at different ages (15W, 20W, 30W and 68W) and identified as a loop structure from EML1 pre-mRNA, which promoted the expressions of CYP19A1 and StAR and the production of E2 and P4 in follicular granulosa cells (GCs) using qRT-PCR and ELISA. Furthermore, circEML1 was proved to serve as a sponge of gga-miR-449a to participate in the steroidogenesis using the dual luciferase reporter, RNA FISH assays, qRT-PCR and ELISA assays. In addition, we evaluated several potential target genes of gga-miR-449a and found that IGF2BP3 was targeted by gga-miR-449a and promoted steroidogenesis and E2/P4 secretions in GCs, which may act the regulatory role via mTOR/p38MAPK pathways. Meanwhile, we implemented a rescue experiment and demonstrated that gga-miR-449a reversed the promoting role of circEML1 on IGF2BP3 expression and steroidogenesis. Eventually, this study suggested that circEML1/gga-miR-449a/IGF2BP3 axis exerted an important role in the regulation of steroidogenesis and steroid hormones’ production possibly through mTOR/p38MAPK pathways in follicular GCs of chicken and may contribute a better understanding of ceRNA network in the modulatory mechanism of hen’s ovarian development and ovulation cycle.

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Relationship among Egg Productivity, Steroid Hormones (Progesterone and Estradiol) and Ovary in Korean Native Ogol Chicken

Cited by 11 publications

References 0 publications

Effect of zinc oxide, potassium iodide and withdrawal diet as alternative moulting methods on performance of commercial laying hens

Effect of zinc oxide, potassium iodide and withdrawal diet as alternative moulting methods on performance of commercial laying hens

Association among Egg Productivity, Granulosa Layer IGF-I, and Ovarian IGF-I in Korean Native Ogol Chicken

CircEML1 facilitates the steroid synthesis in follicular granulosa cells of chicken through sponging gga-miR-449a to release IGF2BP3 expression

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