Relationship between ABO blood groups and cardiovascular disease in type 1 diabetes according to diabetic nephropathy status

Parente, Erika B.; Harjutsalo, Valma; Lehto, Markku; Forsblom, Carol; Sandholm, Niina; Groop, Per‐Henrik

doi:10.1186/s12933-020-01038-z

Cited by 12 publications

(11 citation statements)

References 39 publications

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“…Parente et al 49 found using multivariate analysis that blood group A was a risk factor for ischemic heart disease in individuals with type 1 DM and microalbuminuria but not in those with macroalbuminuria or end-stage renal disease. A case-control study on women with type 2 DM who were similar in other cardiovascular risk factors demonstrated that blood group AB could be considered a risk factor for developing CAD in these patients.…”

Section: Cardiovascular Diseases In Patients With Comorbiditiesmentioning

confidence: 99%

Cardiovascular Diseases Risk Predictors: ABO Blood Groups in a Different Role

Neshat

Rezaei

Farid

et al. 2022

Cardiology in Review

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Cardiovascular diseases (CVDs) pose a serious threat to people's health, with extremely high global morbidity, mortality, and disability rates. This study aimed to review the literature that examined the relationship between blood groups and CVD. Many studies have reported that non-O blood groups are associated with an increased risk and severity of coronary artery disease and acute coronary syndromes. Non-O blood groups increase the risk and severity of these conditions by increasing von Willebrand factor and plasma cholesterol levels and inducing endothelial dysfunction and inflammation. They have also been linked with increased coronary artery calcification, coronary lesion complexity, and poor collateral circulation. Blood groups also affect the prognosis of coronary artery disease and acute coronary syndrome and can alter the rate of complications and mortality. Several cardiovascular complications have been described for coronavirus disease 2019, and blood groups can influence their occurrence. No studies have found a significant relationship between the Lewis blood group and CVD. In conclusion, people with non-O blood groups should be vigilantly monitored for cardiovascular risk factors as prevention and proper treatment of these risk factors may mitigate their risk of CVD and adverse cardiovascular events.

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Section: Cardiovascular Diseases In Patients With Comorbiditiesmentioning

confidence: 99%

Cardiovascular Diseases Risk Predictors: ABO Blood Groups in a Different Role

Neshat

Rezaei

Farid

et al. 2022

Cardiology in Review

View full text Add to dashboard Cite

show abstract

“…Levels of high sensitivity C-reactive protein and the number of antibiotic purchases per year were significantly higher in the type A group. This suggests some sort of inflammatory/infectious mediator which links the type A blood association to certain outcomes [21] . Additionally, in a study by Oner et al, Type A blood was the most dominant genotype in all diabetic groups in both genders, while type AB was significantly more frequent among T1DM [22] .…”

Section: Ii-increased Manifestations Of Covid-19 In Non-o Individualsmentioning

confidence: 99%

The potential use of ABO blood group system for risk stratification of COVID-19

et al. 2020

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ABO blood groups is a cheap and affordable test that can be immediately retrieved from COVID-19 patients at the diagnosis. There is increasing evidence that non-O blood groups have both higher susceptibility and higher severity of COVID-19 infections. The reason behind such relationship seems elusive. Regarding susceptibility, Non-O individuals have Anti-A antibodies which can prevent viral entry across ACE-2 receptors, moreover, Non-O individuals are at higher risk of autoimmunity, hypercoagulable state, and dysbiosis resulting in an augmented tendency for vascular inflammatory sequelae of COVID-19. We can conclude, on the diagnostic level, that ABO blood groups can be potentially used for risk stratification of affected COVID-19 patients, to anticipate the deterioration of patients at higher risk for complications. On a therapeutic level, plasma from normal O blood group individuals might potentially replace the use of convalescent serum for the treatment of COVID-19.

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“…Although there are conflicting results, the relationship between atherothrombosis and non-O group has been shown in many studies. 11–14 Most of the above mentioned studies focused on coronary artery disease. However, it is well known that coronary artery disease and PAD share similar risk factors and pathogenetic process.…”

Section: Discussionmentioning

confidence: 99%

The association between ABO blood groups and TASC II classification in patients with peripheral artery disease

Günaydın

Yılmaz

2022

Vascular

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Objective The aim of this study was to investigate the association between blood groups and severity of peripheral artery disease (PAD) using TASC II classification. Methods The patients who were diagnosed with PAD were retrospectively analyzed. The patients with 50% or more stenosis in the aorto-iliac or femoro-popliteal region detected by conventional or CT angiography were included in the study. These patients were divided into TASC II A, B, C, and D groups considering the severity of PAD. All patients’ blood groups were recorded and compared between TASC II groups. Results While 38% of the study population was O blood group, 61% were non-O group. On the other hand, 90% of the entire study population were RH positive and 10% were RH negative. Non-O blood ratio was found to be significantly higher in patients with higher TASC II groups. (TASC IIA 51.6% vs. TASC IIB 57.9% vs. TASC IIC 61.3% vs. TASC IID 76.6%, p< .001) However, the frequencies of Rh types were similar in all groups. Multiple logistic regression analysis was applied for determining the predictors of severity and complexity of PAD (TASC II C and TASC II D lesions) Conclusions Our study results revealed a clear association between ABO blood groups and severity of peripheral arterial disease. Non-O blood group was found to be the independent predictor of severe and complex PAD.

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Relationship between ABO blood groups and cardiovascular disease in type 1 diabetes according to diabetic nephropathy status

Cited by 12 publications

References 39 publications

Cardiovascular Diseases Risk Predictors: ABO Blood Groups in a Different Role

Cardiovascular Diseases Risk Predictors: ABO Blood Groups in a Different Role

The potential use of ABO blood group system for risk stratification of COVID-19

The association between ABO blood groups and TASC II classification in patients with peripheral artery disease

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