Relationship between Air Pollution and Regional Longevity in Guangxi, China

Abstract

Air pollution has become a global environmental challenge and poses major threats to human health, particularly for the aging population. However, few studies have investigated the effects of air pollutants on human longevity, especially based on the total regional quantities and sources. Based on investigation of the spatiotemporal variations of three air pollutants (PM10, SO2, and NOx) and three longevity indicators (centenarian ratio, centenarity index, and aging tendency), this study aims to identify the relationship between air pollution and regional longevity in Guangxi Province. Air pollutant and population data from 109 counties and areas of Guangxi were collected from environmental research reports and statistical yearbooks. Cluster and outlier analysis was used to detect the regions with high and low clusters of the longevity indicators and air pollutants. Geographically weighted regression analyses were performed to determine the relationship between longevity and air pollutants. A negative relationship between the air pollutants PM10, SO2, and NOx on the aged population was observed. From a provincial level, industrial sources from the urban areas of cities located in the central province, including Liuzhou, Nanning, Laibing, Guigang and Yulin, were important contributors to the air pollutants PM10, SO2, and NOx, and thus could contribute to negative impacts on regional longevity. The key findings from this study will provide a case for management of air pollutants based on public health policies in China as well as other developing communities.

Neurodegeneration and microvascular dysfunction

“…The Maastricht Study is an observational population-based cohort study. 72 In brief, the study focuses on the aetiology, pathophysiology, complications and comorbidities of diabetes mellitus type 2 and is characterized by an extensive phenotyping approach. 72 Eligible for participation were all individuals aged between 40 and 75 years and living in the southern part of the Netherlands.…”

“…72 In brief, the study focuses on the aetiology, pathophysiology, complications and comorbidities of diabetes mellitus type 2 and is characterized by an extensive phenotyping approach. 72 Eligible for participation were all individuals aged between 40 and 75 years and living in the southern part of the Netherlands. 72 Participants were recruited through mass media campaigns, the municipal registries and the regional Diabetes Patient Registry via mailings.…”

“…72 Eligible for participation were all individuals aged between 40 and 75 years and living in the southern part of the Netherlands. 72 Participants were recruited through mass media campaigns, the municipal registries and the regional Diabetes Patient Registry via mailings. 72 Recruitment was stratified according to known type 2 diabetes status, with an oversampling of individuals with type 2 diabetes for reasons of efficiency.…”

“…72 Participants were recruited through mass media campaigns, the municipal registries and the regional Diabetes Patient Registry via mailings. 72 Recruitment was stratified according to known type 2 diabetes status, with an oversampling of individuals with type 2 diabetes for reasons of efficiency. 72 The present report includes cross-sectional and prospective data from up to n=8,005 participants who completed the baseline survey between November 2010 and January 2019.…”

“…72 Recruitment was stratified according to known type 2 diabetes status, with an oversampling of individuals with type 2 diabetes for reasons of efficiency. 72 The present report includes cross-sectional and prospective data from up to n=8,005 participants who completed the baseline survey between November 2010 and January 2019. 72 All participants underwent a standardized set of measurements that were performed by trained research personnel with state-of-the-art measurement techniques.…”