Relationship between bronchoalveolar lavage fluid and plasma endotoxin activity in calves with bronchopneumonia

Nishi, Yasunobu; Tsukano, Kenji; Otsuka, Marina; Tsuchiya, Masaharu; Suzuki, Kazuyuki

doi:10.1292/jvms.18-0643

Cited by 7 publications

(2 citation statements)

References 19 publications

(25 reference statements)

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“…In other words, it will not be possible to get high milk yields from cows in the future. If the farm creates proper conditions for keeping animals and diseases of young animals (dyspepsia and bronchopneumonia) can be avoided, then reliable promising prerequisites are provided for the optimal age of the first calving of heifers and high milk productivity of cows (Nishi et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Untitled

2023

Ukrainian journal of veterinary sciences

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In the production of broiler poultry products, market operators use intensive technologies that involve the use of various, environmentally friendly nutraceuticals, in particular, probiotic preparations. In the technology of raising broiler chickens, probiotic preparations are necessary as a means for the prevention and treatment of gastrointestinal diseases, stimulating the growth and increasing the productivity of poultry. The purpose of the study is to investigate the effect of probiotic biologics on haematological parameters when it is fed to broiler chickens. The experiment used 20 broiler chickens, which were given a probiotic from 28 to 42 days in the following amounts: 0.5 g/10 dm 3 , 2.0 and 4.0 g/10 dm 3 of water. It was found that the morpho-biochemical parameters of poultry blood corresponded to the physiological standards for broiler chickens of the established age and confirmed the absence of pathophysiological changes in their body. On days 35 and 42 of rearing, an increase in the number of leukocytes from 4.4 to 17.2% and the haemoglobin content by 3.9 and 6.2%, respectively, was observed in the blood of broiler chickens fed the probiotic at a dose of 4.0 g/10 dm 3 compared to the control group. On day 35 of the study, a 1.2-fold increase in total serum protein was observed when drinking a probiotic in poultry, respectively, at doses of 2.0 and 4.0 g/10 dm 3 of water, and on day 42 -1.0 times for its drinking at a dose of 4.0 g/10 dm 3 of water. It was found that the content of inorganic calcium and phosphorus in the poultry blood serum corresponded to physiological limits, which indicates a sufficient level of mineral nutrition in the body of broiler chickens. The absence of changes in the activity of alanine aminotransferase and aspartate aminotransferase, the content of total lipids, cholesterol, and creatinine in the blood serum of broiler chickens of the experimental groups indicates the hepato-and nephronethoxicity of the probiotic. Based on the results obtained, the drug under study can be recommended to increase the resistance of the poultry body and regulate metabolism

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Section: Discussionmentioning

confidence: 99%

Untitled

2023

Ukrainian journal of veterinary sciences

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Section: Introductionmentioning

confidence: 99%

Effectiveness of group therapy of calves for nonspecific bronchopneumonia by aerosol method

Drobot,

Sharandak,

Druz

et al. 2023

Ukrainian journal of veterinary sciences

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Nonspecific bronchopneumonia of calves causes significant economic damage to farms, and therefore, it is important to develop effective therapeutic drugs, especially for group use. Aerosolbased medicines deserve attention. The purpose of the study was to investigate the effectiveness of the group aerosol method of administering the drug “Calfmin” to calves with nonspecific bronchopneumonia. Analogue calves of two to three months of age, both clinically healthy and patients with nonspecific bronchopneumonia, were involved in the experiment. Standard clinical and haematological research methods were used to determine the diagnosis and monitor the functional state of the calves’ bodies. It was found that in the blood of calves with nonspecific bronchopneumonia, an increase in the number of white blood cells was observed by 1.3 times (P<0.05) compared to clinically healthy animals. Their blood also showed an increase in the number of stab and segmented neutrophils by 2.0 times (P<0.05) and 1.6 times (P<0.01), respectively, and a decrease in the number of lymphocytes by 1.3 times (P<0.001) and eosinophils by 1.4 times (P<0.001), respectively. In sick calves, there was a 1.2-fold decrease in the number of red blood cells in the blood (P<0.001) and a 1.2-fold decrease in the haemoglobin content (P<0.001) compared to the control. An improvement in the clinical condition and haematological parameters in sick animals was recorded within 3-5 days, a reduction in the duration of therapy by 1.9-2.0 times, and 100% preservation of all sick calves

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A novel triptolide derivative ZT01 exerts anti-inflammatory effects by targeting TAK1 to prevent macrophage polarization into pro-inflammatory phenotype

Zang

Zhou

et al. 2020

Biomedicine & Pharmacotherapy

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Relationship between bronchoalveolar lavage fluid and plasma endotoxin activity in calves with bronchopneumonia

Cited by 7 publications

References 19 publications

Untitled

Untitled

Effectiveness of group therapy of calves for nonspecific bronchopneumonia by aerosol method

A novel triptolide derivative ZT01 exerts anti-inflammatory effects by targeting TAK1 to prevent macrophage polarization into pro-inflammatory phenotype

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