Relationship between Current Psychological Symptoms and Future Risk of Asthma Outcomes: A 12-Month Prospective Cohort Study

Abstract

Current psychological symptoms, especially anxiety combined with depression, independently predict the future risk of asthma outcomes. Ting Zhou and Lan Wang contributed equally to this study.

Co-morbid psychological dysfunction is associated with a higher risk of asthma exacerbations: a systematic review and meta-analysis

“…There was a significant effect of PD on AE only when the exposure time of PD exceeded 1 year. It should be noted that, in our analysis, anxiety did not have a significant influence on hospitalizations or ED visits because of asthma, and this is inconsistent with our prior study (25). The current analysis on anxiety was limited by a small amount of data, and the effects of anxiety on AE should be further considered.…”

“…For studies with exposure time ≤1 year, the relation between PD and AE was not significant (RR =1.24, 95% CI: 0.96-1.59, P=0.095, I 2 =82.8%, Q=11.65, P=0.003) (11,25,26). For studies with exposure time >1 year, <2, and ≥2 years, the relation between PD and AE was significant, but there was , this study was regarded as three independent studies, separated according to the age of the participants.…”

“…Most have good reliability and validity, but they have varying specificity and sensitivity in different populations with different time frames ( Table S3). The Diagnostic and Statistical Manual of Mental Disorders, 4th edition, is the standard classification of mental disorders used by mental health professionals for patient diagnosis and treatment in the United States and is widely used as the criterion standard in validity studies for many other psychometric scales (21,24,25). The Primary Care Evaluation of Mental Disorder is the origin of several other psychometric scales (21,27,28).…”

“…Ten of these were eligible prospective cohort studies and were included in the analysis (10)(11)(12)(20)(21)(22)(23)(24)(25)(26). The flowchart for screening studies is shown in Figure 1.…”

“…In the included studies, exposure to PD was ascertained according to one of eight psychometric tools (10,12,(21)(22)(23)(24)(25)(26), the International Classification of Diseases, 9th Revision, diagnosis of co-morbidities (21), or patient self-report (11). The eight psychometric tools used were all produced in the 1900s.…”