Relationship Between Electrocardiographic Abnormalities and Periodontal Disease: The Hisayama Study

Shimazaki, Yoshihiro; Kiyohara, Yutaka; Kato, Ikunoshin; Kubo, Michiaki; Iida, Mitsuo; Kinoshita, Toshihiko

doi:10.1902/jop.2004.75.6.791

Cited by 35 publications

(37 citation statements)

References 42 publications

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“…Gingival bleeding is one of the definite risk predictor/markers for periodontal dis ease progression, hence we believe that this is one of the most important positive findings noted in this study that is relevant from a clinical point of view. This observation is in agreement with various other studies, 14,24,26,29,31 however, Persson et al 27 did not agree with this observation.…”

Section: British Dental Journalsupporting

confidence: 86%

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Periodontal disease as a risk factor for acute myocardial infarction. A case-control study in Goans highlighting a review of the literature

2007

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Section: British Dental Journalsupporting

confidence: 86%

“…Multivariate logistic regression analysis confirmed that this parameter signifi cantly correlated with AMI when other risk factors were considered. A similar observation has been noted by many authors, 22,24,27,30,31,33 how ever few others 26,40 have reported no association between PD and CHD.…”

Section: British Dental Journalsupporting

confidence: 83%

Periodontal disease as a risk factor for acute myocardial infarction. A case-control study in Goans highlighting a review of the literature

2007

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“…Studies of prevalence of ECG changes in octogenarians, Pima Indians, and a Japanese population have suggested that the risk for ECG abnormalities increases with the severity of PD. 199,264,265 In a different Japanese cohort study, no correlation between PD and prevalence of electrocardiographic abnormalities was found. 266 Thus, the independent correlation of ECG findings with PD has not been definitively proven.…”

Section: Association Of Periodontitis With Ecg Abnormalitiesmentioning

confidence: 92%

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

Lockhart

Bolger²,

Papapanou³

et al. 2012

Circulation

892

814

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Abstract-A link between oral health and cardiovascular disease has been proposed for more than a century. Recently, concern about possible links between periodontal disease (PD) and atherosclerotic vascular disease (ASVD) has intensified and is driving an active field of investigation into possible association and causality. The 2 disorders share several common risk factors, including cigarette smoking, age, and diabetes mellitus. Patients and providers are increasingly presented with claims that PD treatment strategies offer ASVD protection; these claims are often endorsed by professional and industrial stakeholders. The focus of this review is to assess whether available data support an independent association between ASVD and PD and whether PD treatment might modify ASVD risks or outcomes. It also presents mechanistic details of both PD and ASVD relevant to this topic. The correlation of PD with ASVD outcomes and surrogate markers is discussed, as well as the correlation of response to PD therapy with ASVD event rates. Methodological issues that complicate studies of this association are outlined, with an emphasis on the terms and metrics that would be applicable in future studies. Observational studies to date support an association between PD and ASVD independent of known confounders. They do not, however, support a causative relationship. Although periodontal interventions result in a reduction in systemic inflammation and endothelial dysfunction in short-term studies, there is no evidence that they prevent ASVD or modify its outcomes. (Circulation. 2012;125:2520-2544.)

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“…1,11 It is also known that subjects with advanced CP are characterized by increased left ventricular mass (LVM). [12][13][14] However, the reason for this increase is not clear. A simple path that leads from increased arterial stiffness caused by inflammatory cytokines-induced arteriosclerosis, to a resultant increase of blood pressure and at the end to increased LVM, is not confirmed.…”

mentioning

confidence: 99%

Association of Chronic Periodontitis With Left Ventricular Mass and Central Blood Pressure in Treated Patients With Essential Hypertension

Franek

Klamczyńska

Ganowicz

et al. 2009

American Journal of Hypertension

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Relationship Between Electrocardiographic Abnormalities and Periodontal Disease: The Hisayama Study

Abstract: This study clearly shows the relationship between periodontitis and ECG abnormalities, which are important predictors of CVD.

Cited by 35 publications

References 42 publications

Periodontal disease as a risk factor for acute myocardial infarction. A case-control study in Goans highlighting a review of the literature

Periodontal disease as a risk factor for acute myocardial infarction. A case-control study in Goans highlighting a review of the literature

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

Association of Chronic Periodontitis With Left Ventricular Mass and Central Blood Pressure in Treated Patients With Essential Hypertension

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