Relationship between Elevated Levels of Resistin and Prothrombotic State in Type 2 Diabetes Mellitus

Korzh, Oleksii; Krasnokutskiy, S.; Lavrova, Yelizaveta

doi:10.1016/j.metabol.2020.154494

Cited by 1 publication

(1 citation statement)

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“…Initially, resistin was believed to promote insulin resistance, T2DM, and obesity by inducing lipolysis in adipocytes. However, recent studies have shown no statistical significance in detecting increased resistin levels in a prothrombotic state, such as in T2DM [101,102].…”

Section: Resistinmentioning

confidence: 98%

The Role of Adipokines in the Pathologies of the Central Nervous System

Huber,

Szerenos,

Lewandowski

et al. 2023

IJMS

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Adipokines are protein hormones secreted by adipose tissue in response to disruptions in physiological homeostasis within the body’s systems. The regulatory functions of adipokines within the central nervous system (CNS) are multifaceted and intricate, and they have been identified in a number of pathologies. Therefore, specific adipokines have the potential to be used as biomarkers for screening purposes in neurological dysfunctions. The systematic review presented herein focuses on the analysis of the functions of various adipokines in the pathogenesis of CNS diseases. Thirteen proteins were selected for analysis through scientific databases. It was found that these proteins can be identified within the cerebrospinal fluid either by their ability to modify their molecular complex and cross the blood–brain barrier or by being endogenously produced within the CNS itself. As a result, this can correlate with their measurability during pathological processes, including Alzheimer’s disease, amyotrophic lateral sclerosis, multiple sclerosis, depression, or brain tumors.

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Section: Resistinmentioning

confidence: 98%