2018
DOI: 10.1002/jor.23836
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Relationship between glenoid deformity and gait characteristics in a rat model of neonatal brachial plexus injury

Abstract: Our findings link musculoskeletal changes and functional outcomes in an NBPI rat model. Thus, gait analysis is a potentially useful, non-invasive, quantitative way to investigate the effects of injury and deformity on limb function in the NBPI rat model. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1991-1997, 2018.

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(4 citation statements)
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“…Furthermore, investigating the fidelity with which passive outcomes can predict functional performance in rodents may increase utility of passive performance data and elucidate mechanisms contributing to neuromotor and musculoskeletal deficits. Existing literature on functional movement following BPBI in rodent models includes qualitative reports of altered forelimb posture following preganglionic 8 and postganglionic injury, 13 and quantitative stride and stance metrics following postganglionic injury 14 . The quantitative effects of injury location on functional limb posture and muscle excursion have not been previously studied.…”
Section: Introductionmentioning
confidence: 99%
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“…Furthermore, investigating the fidelity with which passive outcomes can predict functional performance in rodents may increase utility of passive performance data and elucidate mechanisms contributing to neuromotor and musculoskeletal deficits. Existing literature on functional movement following BPBI in rodent models includes qualitative reports of altered forelimb posture following preganglionic 8 and postganglionic injury, 13 and quantitative stride and stance metrics following postganglionic injury 14 . The quantitative effects of injury location on functional limb posture and muscle excursion have not been previously studied.…”
Section: Introductionmentioning
confidence: 99%
“…Two potential useful tools for studying functional movement ex vivo are gait analysis and musculoskeletal modeling. Gait analysis can be an effective function‐based quantitative method for studying BPBI in a rat model 14 . Musculoskeletal models provide a framework for integrating anatomical and physiological data, offering insight into the biomechanics underlying movement.…”
Section: Introductionmentioning
confidence: 99%
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