Relationship between hepatitis C virus аnd cardiovascular disease

Abstract

Aim. To present the literature data on the features of the development and progression of cardiovascular diseases (CVD) in patients with chronic hepatitis C. Key points. The latest data on the relationship of hepatitis C virus (HCV) with the development and course of cardiovascular diseases (CVD) are presented, clinical manifestations and pathogenesis are described, damage to the cardiovascular system in HCV-associated cryoglobulinemia and issues of heart transplantation from HCV-infected donors are highlighted. Conclusion. Hepatitis C virus is a risk factor for the development and progression of various CVD, which is associated with an increased mortality rate of patients, including due to cardiovascular causes. The pathogenetic mechanisms of the virus' effect on the cardiovascular system are diverse and require further study. Increasing the availability of antiviral therapy will have a positive effect on reducing the risk of developing CVD. Heart transplantation from HCV-infected donors is not currently a problem for global health, which can be used to increase the availability of heart transplants for patients in need. Key words: chronic hepatitis C, cardiovascular system, heart, cryoglobulinemia, transplantation.