Relationship between metabolic syndrome components and vascular properties in Japanese type 2 diabetic patients without cardiovascular disease or nephropathy

In Addition to Insulin Resistance and Obesity, Brachial-Ankle Pulse Wave Velocity is Strongly Associated with Metabolic Syndrome in Chinese - A Population-Based Study (Taichung Community Health Study, TCHS)

“…The cut-off values of baPWV to predict diabetes, hypertension, and MetS were found to be higher than Yamashina's suggestion. Although the association between MetS and arterial stiffness had been proved by many studies 11,[17][18][19][20] , there seems to be a gender difference. For example, a previous study in Korea found that MetS is associated with baPWV in women, but not in men 21) .…”

Association between the time of length since smoking cessation and insulin resistance in asymptomatic Korean male ex-smokers

“…Early vascular alterations, such as increased arterial stiffness and vascular endothelial cell injury, might be responsible for the development of the metabolic syndrome [32,33]. Smoking may indeed accelerate those pathways.…”

Cardiovascular Risk Assessment in Diabetes and Chronic Kidney Diseases: A New Insight and Emerging Strategies

“…Although insulin resistance and hyperinsulinemia can be attributed to these complications, they may occur with or without insulin resistance because several other mechanisms including advanced glycation end products, autonomic nervous instability, imbalance between the renin-angiotensin system and nitric oxide, hemodynamic changes and endothelial dysfunction with subsequent ADMA accumulation (an inhibitor for nitric oxide synthesis) and adiponectin deficiency also contribute in the process [120,129,130]. Furthermore, albuminuria, arterial stiffness and intima media thickness increase with the increasing number of metabolic syndrome components even before fulfilling the diagnostic criteria for the syndrome, particularly amongst subjects with type 2 DM [131]. In addition,…”

“…It is also closely associated with the prevalence of anaemia [128] , hypertension [157] and metabolic syndrome components [131]. Microalbuminuria commonly occurs early in subjects with abnormal glucose metabolism [147,158] and is correlated with dyslipidemia [159], arterial stiffness [160,161] and increased coagulability [162] as well as inflammatory www.intechopen.com markers [163,164].…”

“…For instance the number of present components of the metabolic syndrome associated with the risk of CV disease in DM or the development of renal impairment [82,83]. Alternatively, each factor can be graded in an individual patient and scored (e.g.…”