Relationship between Retinal Lesions and Axial Length, Age and Sex in High Myopia

Abstract

We analysed the relationship between central and peripheral retinal lesions and axial length (AL), patient's age and sex with myopia greater than 6 diopters. A total of 212 eyes of 109 patients with high myopia underwent detailed funduscopy and A-scan ultrasonography. AL was measured, and central and peripheral retinal lesions were noted. Results were analysed using Student's t-test. Sixty-one patients (118 eyes) were female and 48 (94 eyes) male. Mean age was 31.00 +/- 13.67 years, and mean AL was 28.31 +/- 2.02 mm. Chorioretinal atrophy, Fuchs' spot, posterior staphyloma and posterior vitreous detachment increased significantly with AL and age. Fuchs' spot was more common in females. White-without-pressure (WWP) was inversely correlated with AL and age, and was more common in males. The high frequency of WWP in younger patients and moderate AL suggests that these lesions result from vitreoretinal tractions. Lattice degeneration was also a frequent finding in high myopia, and tended to increase with AL and age, though without reaching statistical significance.

Prevalence of myopic retinopathy in rural Central India

“…As in the previous studies, the prevalence of myopic retinopathy in our study increased with the amount of myopia (Gözüm et al. ; Liu et al. ; Neelam et al.…”

The types and severity of high myopic maculopathy in Chinese patients

“…Vongphanit et al. 12 examined 3585 participants and found the prevalence of myopic retinopathy increased with higher levels of myopia, from 1.0% of right eyes with myopia <−3.0 D to 52.4% of right eyes with myopia of at least −9.0 D. Earlier studies also showed a higher prevalence of pathological signs associated with greater axial lengths, 9,25 and many studies have shown that high myopia is generally axial in nature 26 . Several studies have demonstrated decreased ocular pulse and retinal blood flow with increasing myopia 27 .…”

“…The associated lesions include a tessellated fundus, lacquer cracks, choroidal neovascularisation (CNV), and chorioretinal atrophy. Several risk factors for myopic maculopathy have been identified: axial length, posterior staphyloma, and the severity of myopia 8,9 . However, most large‐scale studies have been conducted in western countries and the Japanese population, 5,8–15 with limited assessment of risk factors for the different types and severity of high myopic maculopathy.…”

“…Several risk factors for myopic maculopathy have been identified: axial length, posterior staphyloma, and the severity of myopia 8,9 . However, most large‐scale studies have been conducted in western countries and the Japanese population, 5,8–15 with limited assessment of risk factors for the different types and severity of high myopic maculopathy. Due to the increasing incidence and poor long‐term prognosis of high myopic maculopathy, it is important to evaluate these features of high myopic maculopathy and their associated risk factors in the Chinese population.…”

Miopia na Infância

“…As alterações na retina decorrentes de miopia maior que 6 D aumentam com o tamanho do globo e com a idade 31 . A progressão da miopia pode acarretar alterações oculares irreversíveis e perda da visão.…”