Relationship Between Smoking, Nutritional Status, and Renal Function in Patients With Arterial Hypertension

Boiko, Olha; Родіонова, В. В.

doi:10.1016/j.chest.2020.08.155

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“…Polymorbidity is one of the features of the modern clinical picture of internal diseases, and arterial hypertension (AH) and chronic obstructive pulmonary diseases remain the most common diseases of the adult population of developed countries [1]. One of the most common nosological forms is chronic obstructive pulmonary disease (COPD) [2,3]. According to WHO experts, by 2030, COPD will become the third leading cause of death worldwide [2,4].…”

Section: Introductionmentioning

confidence: 99%

“…The most significant correlation was found between COPD and car-diovascular disease. It has been established that COPD is a precursor to the development of cardiovascular diseases and / or its exacerbation [2,3,4,5]. It was found that there is a relationship between an increase in arterial wall stiffness and the severity of bronchial obstruction in patients, and a decrease in FEV1 is associated with a high risk of cardiovascular mortality [2,5].…”

Section: Introductionmentioning

confidence: 99%

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Aggravating Effect of Arterial Hypertension on the Course of Chronic Obstructive Pulmonary Disease in Patients With Comorbid Pathology

Родіонова

Boiko

2021

Wiad Lek

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The aim: To study the effect of arterial hypertension on the course of chronic obstructive pulmonary disease in patients with comorbid pathology. Materials and methods: The prospective study included 61 patients with COPD: 32 stable male patients with COPD with comorbid arterial hypertension of stage II 1-3 degrees and 29 stable outpatients of men with COPD of clinical groups A-D with impaired respiratory function II-IV according to GOLD. All patients, in accordance with the goals and objectives of the study, were divided into 2 groups: group I consisted of men with isolated COPD, middle age – 56.0 (8.5) years, average duration of the disease – 16.2 (1.3) years, Group II consisted of male patients with COPD and arterial hypertension (AH), middle age – 59.5 (7.5). The patients underwent a general clinical examination, which included an assessment of complaints, anamnestic data, and a physical examination. The severity of COPD was determined on the basis of the frequency of exacerbations during the year, assessment of dyspnea using the mMRS scale, spirographic data. Statistical materials were processed using the STATISTICA 10.0 program. Results: In group I, 20 patients (69%) complained of dyspnea during exercise, in group II – 25 patients (78%) (p = 0.4), 28 patients (96.5%) complained of cough with vague sputum. group and 30 patients in group II (93.8%) (p = 0.09). When assessing the number of exacerbations over the past year, it was determined that patients with isolated COPD had an average of 1.0 (1.0; 2.0) exacerbations, and patients with COPD and AH – 2.0 (1.0; 3.0 ) (p = 0.06). According to the CAT questionnaire, the following data were obtained: in group I – 9.0 (8.0; 11.0) points, and in group II – 17.5 (10.0; 20.0) points (p = 0.02). When conducting spirographic studies, a statistically significant more expressive bronchial obstruction was found in patients with COPD and comorbid hypertension. Conclusions: The presence of comorbid arterial hypertension leads to the intermittent effect of diseases: according to the results of mMRC and SAT test, ailments for COPD were examined, they have a more severe course of underlying seizure in the presence of concomitant arterial hypertension. Clinical manifestations in patients with COPD and H are more severe compared to clinical manifestations in patients without aggravated diseases of the cardiovascular system. Concomitant arterial hypertension enhances the manifestations of bronchial obstruction, in the same way as with patients with isolated COPD.

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Section: Introductionmentioning

confidence: 99%