Relationship between Spinal Hemangioblastoma Location and Age

Abstract

Study DesignRetrospective case series.PurposeTo investigate the relationship between tumor location and clinical characteristics.Overview of LiteratureHemangioblastoma is a rare disease that develops in the central nervous system. Magnetic resonance imaging (MRI) is useful to evaluate hemangioblastomas. Hemangioblastoma's location is designated as intramedullary, intramedullary+extramedullary, or extramedullary by MRI.MethodsWe analyzed 11 patients who underwent surgery for spinal hemangioblastoma. Using T1 contrast axial MRI data, the cases were divided into three groups (intramedullary, intramedullary+extramedullary, and extramedullary). Patient demographics, MRI findings, and preoperative neurological status were analyzed and compared for each group.ResultsThe average age of patients with intramedullary, intramedullary+extramedullary, and extramedullary hemangioblastoma was 34.0, 64.4, and 67.5 years, respectively. Patients in the intramedullary hemangioblastoma group were younger than the other groups. Extramedullary cases had a smaller syrinx compared to the other groups.ConclusionsAge may play an important role in the hemangioblastoma tumor location and the subsequent diagnosis by an MRI.

Intradural extramedullary hemangioblastoma of the thoracic cord: A case report

“…[ 3 - 5 ] Of interest, Yasuda et al . reported that extramedullary hemangioblastomas had smaller syrinxes versus intramedullary and intramedullary+extramedullary lesions,[ 6 ] this finding might help distinguish between extramedullary hemangioblastomas versus meningioma and other tumors.…”

Hemangioblastoma Puramente Extradural Simulando Meningioma: relato de caso e revisão de literatura

“…Há predominância no sexo masculino na relação de 2:1 1 , com variação na literatura até 5,5:1 10 e ocorrência em adultos jovens, com pico de incidência entre 35 e 45 anos. Yasuda et al 10 descreveram uma maior média de idade em hemangioblastomas extramedulares puros em comparação aos intramedulares e intra/extramedulares. Hemangioblastomas extradurais puros são raros com apenas quatro casos descritos na literatura mundial 7 .…”

“…A RM é padrão-ouro no diagnóstico de hemangioblastoma do canal espinhal, o tumor em comparação com a medula espinhal apresentando-se de hipo-a isointenso nas sequências ponderadas em T1, captação de contraste, e de iso-a hiperintenso nas sequências ponderadas em T2, os extramedulares não causam alteração no sinal 10,17,22 .…”

“…Yasuda et al 22 corroboram quanto ao uso de angiografia e embolização da coluna vertebral pré-operatória com objetivo de determinar a localização e a natureza do tumor e a anatomia da artéria alimentar e delinear o suprimento vascular.…”

Nontraumatic Emergency of the Spine

“…14,15 There are two main different types: at the cervical level it is usually the cellular type, and at the level of the conus ependymoma it is usually the myxopapillary type. They are slow-growing tumors and characteristically show vertebral scalloping with enlarged foramen, erosion of the pedicle or laminar thinning, intratumoral cyst, and hemorrhage with sometimes fluid-fluid levels 16 (►Figs. 5 and 6).…”