Organ-on-a-chip (OOC) systems are engineered nanobiosystems
to
mimic the physiochemical environment of a specific organ in the body.
Among various components of OOC systems, biomimetic membranes have
been regarded as one of the most important key components to develop
controllable biomimetic bioanalysis systems. Here, we review the preparation
and characterization of biomimetic membranes in comparison with the
features of the extracellular matrix. After that, we review and discuss
the latest applications of engineered biomimetic membranes to fabricate
various organs on a chip, such as liver, kidney, intestine, lung,
skin, heart, vasculature and blood vessels, brain, and multiorgans
with perspectives for further biomedical applications.