Relationship between the CHADS2 score and risk of very late recurrences after catheter ablation of paroxysmal atrial fibrillation

High-density lipoprotein cholesterol and left atrial or left atrial appendage thrombus in non-valvular atrial fibrillation patients

“…Recently, CHADS 2 score has been found to be associated with an increased risk of AF recurrence following RFCA and LA or LAA thrombus formation in AF patients [4,5]. In our present study, although thrombus group have a higher CHADS 2 score, multivariate logistic regression analysis indicated that there is no statistical significance.…”

Effect of Radiofrequency Catheter Ablation for Atrial Fibrillation on Morbidity and Mortality

“…An advantage of this restriction was to avoid contamination of the diagnostic codes, which might be carried in the following years and misinterpreted as a new event after RFA. Because the patients with higher CHADS2 scores are associated with an increased risk of AF recurrence after RFA, 27 it is also difficult to speculate how the results might change among these patients with a higher risk of stroke. Second, because the data source was a nationally sponsored claims database, the immediate outcome or procedural success of RFA (eg, the percentage of successful sinus rhythm restorations) was not available.…”

Oral anticoagulation is frequently discontinued after ablation of paroxysmal atrial fibrillation despite previous stroke: data from the German Ablation Registry

“…Therefore, patients who were considered to have had a successful ablation procedure may experience late arrhythmia recurrence and are then again at high risk for TE due to underlying risk factors. In one study, late recurrences were even more frequent in patients with high CHADS 2 -Score [15]. Increase of ASA therapy during FU might be related either to changing OAC to ASA or to discontinuation of OAC and prescription of ASA due to comorbidities, such as coronary artery disease.…”

“…AF might even only be a risk marker for TE rather than the cause [14]. Moreover, as procedural success rates of AF-ablation still need to improve and even late recurrences after several years are observed [15], the definition of long-term ablation success remains difficult. Therefore, patients who were considered to have had a successful ablation procedure may experience late arrhythmia recurrence and are then again at high risk for TE due to underlying risk factors.…”