Relationship Between the Content of Androgenic Steroids in the Testes and the Secretory Activity of the Seminal Vesicles in the Bull

Abstract

SUMMARY Testosterone and androstenedione were determined chemically in testes of bulls ranging in age from 28 days to 17½ years. The earliest age at which it was possible to detect both steroids was 39 days. Their combined contents in the testes varied from 4·7 to 61 μg at 39–90 days, from 31 to 475 μg at 3½–5½ months, and from 155 to 3450 μg at 10½ months-17½ years of age. The ratio androstenedione/testosterone decreased with age. In immature bull calves, less than 4 months old, it exceeded 1:1, in animals above 9 months of age it was less than 1:10. The appearance of chemically demonstrable amounts of testosterone and androstenedione in the testes of young bull calves coincided with the onset of an active process of fructose and citric-acid production by the seminal vesicles. Between the 2nd and 6th month of life, the weight, fructose level and citric-acid level of the seminal vesicles increased at an exponential rate, and this sharp increase in the activity of the seminal vesicles was accompanied by a similarly sharp increase in the testosterone content of the testes. In adult bulls, differing widely in age and breed, the testicular content of testosterone was significantly correlated with the weight, fructose content and citric-acid content of the seminal vesicles.

Seasonal variation in the histology of the testis of the red deer, Cervus elaphus

“…Dissection of the animals and recovery of tissues was as described previously (Lincoln, 1971b). Frozen samples of seminal vesicles were assayed for fructose by a colorimetrie method (Lindner & Mann, 1960). The samples of testicular tissue were assayed for testosterone by a specific gas Chromatographie technique (Mann, Rowson, Short & Skinner, 1967), and the blood serum levels of LH were determined by radioimmunoassay (Scaramuzzi, Caldwell & Moor, 1970).…”

The reproductive cycle in the male hedgehog (Erinaceus europaeus L.) : a study of endocrine and exocrine testicular functions

“…Gonadal (Allanson, 1963), roebuck (Short and Mann, 1966), ferret (Ishidci, 1968), red-deer (Lincoln, 1971), stoat (Gulamhusein and Tam, 1974), polecat, marten, stone-marten (Audy, 1976) and red fox (Joffre, 1976) (Allanson, 1934 ;Scure, 1969 ;Saboureau and Peyre, 1970). Moreover, the determination of fructose and citric acid contents in hedgehog accessory glands, which are related to the concentrations of circulating androgens (Lindner and Mann, 1960), are good criteria for testing the accuracy of periods of maximal activity and quiescence. The present data complete previous results (Saboureau and Peyre, 1970) (Saboureau and Boissin, 1978a, b).…”

Reflections on the attainment of puberty in the rat: have circadian signals a role to play in its onset?

“…In the young rat, as in the guinea-pig (Becher & Snipes, 1968) and the bull (Lindner & Mann, 1960), androstenedione is secreted in larger amounts by the testis than is testosterone (Nayfeh & Baggett, 1966;Ficher & Steinberger, 1971;Moger, 1975). This is apparently due to the ability of testicular tissue in the young rat, especially between 20 and 30 days of age, to convert testosterone precursors preferentially to 5ct-reduced androgens, e.g.…”