Relationship Between the Elevated Muscle FDG Uptake in the Distal Upper Extremities on PET/CT Scan and Prescan Utilization of Mobile Devices in Young Patients

Bai, Xia; Wang, Xuemei; Zhuang, Hongming

doi:10.1097/rlu.0000000000001967

Cited by 17 publications

(7 citation statements)

References 25 publications

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“… In pediatric patients all the above rules, according to pathology, should be followed. Limiting the use of mobile devices for playing is important [ 269 ]. [ 18 F]FDG activity should be calculated according to the EANM pediatric dosage card [ 270 ].…”

Section: Resultsmentioning

confidence: 99%

State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation

Casali

Lauri

Altini

et al. 2021

Clin Transl Imaging

103

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Aim The diagnosis, severity and extent of a sterile inflammation or a septic infection could be challenging since there is not one single test able to achieve an accurate diagnosis. The clinical use of 18F-fluorodeoxyglucose ([ 18 F]FDG) positron emission tomography/computed tomography (PET/CT) imaging in the assessment of inflammation and infection is increasing worldwide. The purpose of this paper is to achieve an Italian consensus document on [ 18 F]FDG PET/CT or PET/MRI in inflammatory and infectious diseases, such as osteomyelitis (OM), prosthetic joint infections (PJI), infective endocarditis (IE), prosthetic valve endocarditis (PVE), cardiac implantable electronic device infections (CIEDI), systemic and cardiac sarcoidosis (SS/CS), diabetic foot (DF), fungal infections (FI), tuberculosis (TBC), fever and inflammation of unknown origin (FUO/IUO), pediatric infections (PI), inflammatory bowel diseases (IBD), spine infections (SI), vascular graft infections (VGI), large vessel vasculitis (LVV), retroperitoneal fibrosis (RF) and COVID-19 infections. Methods In September 2020, the inflammatory and infectious diseases focus group (IIFG) of the Italian Association of Nuclear Medicine (AIMN) proposed to realize a procedural paper about the clinical applications of [ 18 F]FDG PET/CT or PET/MRI in inflammatory and infectious diseases. The project was carried out thanks to the collaboration of 13 Italian nuclear medicine centers, with a consolidate experience in this field. With the endorsement of AIMN, IIFG contacted each center, and the pediatric diseases focus group (PDFC). IIFG provided for each team involved, a draft with essential information regarding the execution of [ 18 F]FDG PET/CT or PET/MRI scan (i.e., indications, patient preparation, standard or specific acquisition modalities, interpretation criteria, reporting methods, pitfalls and artifacts), by limiting the literature research to the last 20 years. Moreover, some clinical cases were required from each center, to underline the teaching points. Time for the collection of each report was from October to December 2020. Results Overall, we summarized 291 scientific papers and guidelines published between 1998 and 2021. Papers were divided in several sub-topics and summarized in the following paragraphs: clinical indications, image interpretation criteria, future perspectivess and new trends (for each single disease), while patient preparation, image acquisition, possible pitfalls and

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Section: Resultsmentioning

confidence: 99%

State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation

Casali

Lauri

Altini

et al. 2021

Clin Transl Imaging

103

View full text Add to dashboard Cite

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“…A follow-up PET/CT 1 year after stem cell transplantation was performed to evaluate the therapy response. The images did not show any abnormal 18 F-FDG accumulation in skeletal muscle, suggesting complete resolution. CAEBV infection is a severe disease with high morbidity and mortality.…”

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confidence: 81%

“…18 F-FDG PET/CT was performed to guide the lymph node biopsy and help differential diagnosis, 1 which did not show abnormal activity in the lymph nodes, liver, or spleen. Unexpectedly, heterogeneously 18 F-FDG uptake associated with mild swelling in multiple skeletal muscle groups was noted, especially in the right upper arm (small arrows in A-D; A: MIP; B: PET; C: CT; D: fusion), the right thigh (middle arrows in A, E, F, and G), the left thigh (large arrows in A, H, I, and J), and the right foot (dotted arrows in A, K, L, and M). In order to determine the stage of the CAEBV infection, 2,3 a left cervical lymph node biopsy was performed.…”

mentioning

confidence: 99%

“…13,14 18 F-FDG PET/CT has been used in the diagnosis and therapy response evaluation of EBV infection related disorder and showed advantages compared with anatomical imaging methods. 1,15,16 On the other hand, FDG uptake by muscle on PET/CT can be caused by physiological process, [17][18][19][20] myositis, 21,22 or malignant disease. 23 Skeletal muscle involvement caused by CAEBV infection should be included as differential diagnoses on 18 F-FDG PET/CT scan.…”

mentioning

confidence: 99%

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Muscle Involvement Caused by Chronic Active Epstein-Barr Virus Infection on 18F-FDG PET/CT in a Pediatric Patient

Yang

Kan

et al. 2021

Clin Nucl Med

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A 7-year-old girl with chronic active EBV (CAEBV) infectionassociated hemophagocytic lymphohistiocytosis presented with fever. 18 F-FDG PET/CT revealed heterogeneous FDG uptake in multiple muscle groups without significant abnormal activity elsewhere. On repeat FDG PET/CT scan 1 year later after therapy, the abnormal activity in muscles disappeared. Skeletal muscle involvement by CAEBV infection should be included as differential diagnosis for increased muscle activity on FDG PET/CT study.

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“…Consequently, the submental activity was interpreted as genioglossus muscle activity due to sucking on a pacifier. Elevated FDG activity in the major muscles due to exertion is well-described [6][7][8][9][10] and rarely causes diagnostic dilemma. However, focal genioglossus muscle activity due to sucking in toddlers was much less recognized.…”

mentioning

confidence: 99%

Increased Genioglossus Muscle FDG Activity Due to Using Pacifier

Tong

Zhuang

2022

Clin Nucl Med

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An 18-month-old girl with history of liver transplant underwent FDG PET/CT to evaluate posttransplant lymphoproliferative disorder. In addition to multistation hypermetabolic lymphadenopathy and abnormal activity in the liver, stomach, and small bowel, in keeping with known posttransplant lymphoproliferative disorder, the images also showed focal activity in the submental region. This submental activity persisted on 2 separate follow-up FDG PET/CT studies, even though other foci of abnormal activity resolved after chemotherapy. Records revealed that the patient was sucking on a pacifier prior to all 3 FDG PET/CT studies, and the submental uptake corresponded with genioglossus muscle activity.

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Relationship Between the Elevated Muscle FDG Uptake in the Distal Upper Extremities on PET/CT Scan and Prescan Utilization of Mobile Devices in Young Patients

Abstract: Increased FDG uptake in the muscles of the DUEs in young patients is commonly seen in those who used mobile devices prior to PET/CT study. Recommendation should be considered to reduce using mobile devices prior to FDG PET/CT study in young patient population.

Cited by 17 publications

References 25 publications

State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation

State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation

Muscle Involvement Caused by Chronic Active Epstein-Barr Virus Infection on 18F-FDG PET/CT in a Pediatric Patient

Increased Genioglossus Muscle FDG Activity Due to Using Pacifier

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