Relationship between the triglyceride-glucose index and the SYNTAX score 2 in patients with non-ST elevation myocardial infarction

Abstract

Objective We evaluated if admissiontriglyceride-glucose index (TyG index) correlated with the anatomical synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score 2 in non-ST elevation myocardial infarction (NSTEMI), nondiabetic patients. Methods SYNTAX score 2 (SSII) was retrospectively evaluated in 260 nondiabetic patients hospitalized with NSTEMI who underwent coronary angiography. The TyG index was calculated using the following equation: log [fasting triglycerides (mg/dl) × fasting glucose (mg/dl)/2]. We stratified patients according to tertiles of SSII (≤21.5, 21.5–30.6, and ≥30.6). These score ranges were defined as SSII low, SSII mid, and SSII high, respectively. Results The average age of the patients was 57.2 ± 10.9 years; 135 patients (52.2%) were males. The average TyG index was 8.68 ± 0.12, and SSII was 18.9 ± 9.9. A moderate correlation was found between TyG index and SSII ( r = 0.347; P < 0.001) and TyG index was independent risk factors for SSII high [odds ratio (OR), 6.0; 95% CI, 2.7–17.0; P < 0.001]. Conclusion In nondiabetic patients with NSTEMI, TyG index correlated with the SSII.

Clinical Significance of the Triglyceride-Glucose Index in Patients Requiring Nonsurgical Intensive Care

“…9,16,22) The TyG index was independently correlated with coronary artery severity (Synergy between PCI with Taxus and Cardiac Surgery [SYNTAX] score). 16,17,23) Addition of the residual SYNTAX score and TyG index to the baseline risk model had an incremental effect on the predictive ability for major adverse cardiac events (increase in the Cstatistic value from 0.660 to 0.732; integrated discrimination improvement 0.018; continuous net reclassification improvement 0.274). The TyG index accurately indicates the degree of coronary artery stenosis, calcification, and atherosclerosis.…”

Role of simple inflammatory parameters in predicting the severity of coronary artery disease

“…The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) score is an indicator of the complexity of coronary artery disease. Various clinical outcomes in non-ST elevation myocardial infarction (NSTEMI) patients have been extensively studied using the SYNTAX score II, and this score is a reliable indicator of mortality in patients with acute coronary syndrome (ACS) who underwent PCI 1 . However, the SYNTAX score is an angiographic scoring system.…”