Relationships Between Cognitive Deficits, Symptoms and Quality of Life in Schizophrenia

Savilla, Kara; Kettler, Lisa; Galletly, Cherrie

doi:10.1080/00048670802050512

Cited by 97 publications

(57 citation statements)

References 40 publications

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“…In the study, stepwise regression analyses when using several clinical variables including the BACS scores as independent variables showed that the QLS total score was significantly predicted by the PANSS negative syndrome scale score, the CDSS score, and the BACS Attention and speed of information processing score. The results were rather consistent with those of previous researches in terms of that cognitive dysfunction was on the whole related to lowered objective QOL (28,30,37).…”

Section: Relation Between Cognitive Func-tion and Quality Of Lifesupporting

confidence: 83%

“…Some previous research groups have investigated the relation between QOL and cognitive function in people with schizophrenia, and reported the significant correlations between QOL and some domains of cognitive function such as verbal memory, vocabulary, fluency performance, attention, social knowledge, and executive function (12,28,(29)(30)(31)(32).…”

Section: Relation Between Cognitive Func-tion and Quality Of Lifementioning

confidence: 99%

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Quality of life and its predictors in people with schizophrenia

Tomotake

2011

J. Med. Invest.

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Section: Relation Between Cognitive Func-tion and Quality Of Lifesupporting

confidence: 83%

Section: Relation Between Cognitive Func-tion and Quality Of Lifementioning

confidence: 99%

Quality of life and its predictors in people with schizophrenia

Tomotake

2011

J. Med. Invest.

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“…In fact, the correlation between cognition as assessed by SCoRS and quality of life found in our study is stronger than that reported by studies that used neuropsychological tests [30][31][32][33] and by a meta-analysis. 14 Other studies have reported similar results, with interview-based assessment of cognition tending to correlate more strongly with quality of life than performance-based measures.…”

Section: Discussioncontrasting

confidence: 55%

“…Most of those studies, however, used neuropsychological tests to assess cognition. 14,[30][31][32][33] Hence, our results indicate that interview-based instruments are also suitable to detect the impact of cognitive impairment on quality of life. This kind of cognitive assessment has obvious advantages over neuropsychological evaluation, especially in clinical settings, since it is easier, faster and does not require extensive training.…”

Section: Discussionmentioning

confidence: 90%

Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms

Cruz

Resende

Carvalhaes³

et al. 2016

Rev. Bras. Psiquiatr.

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Objective: To analyze the correlation between quality of life, symptoms, and cognition assessed by the interview-based Schizophrenia Cognition Rating Scale (SCoRS). Methods: Seventy-nine outpatients diagnosed with schizophrenia were evaluated with the Quality of Life Scale -Brazilian version (QLS-BR), the SCoRS, and symptoms scales (Positive and Negative Syndrome Scale [PANSS]). After determining the potential explanatory variables using Spearman's correlation and Student's t test results, we ran simple, multivariate, and decision-tree regression analyses to assess the impact of SCoRS and PANSS ratings on mean overall quality of life. Results: Cognitive deficits and negative symptoms were the best predictors of quality of life. A low degree of negative symptoms (PANSS negative o 11) was a strong predictor of better quality of life (QLS B 75), regardless of SCoRS rating. Among participants with more severe negative symptoms, elevated cognitive impairment (interviewer SCoRS B 44) was a predictor of worse quality of life (QLS B 44). Conclusions: Cognitive impairment determined by interview-based assessment seems to be a strong predictor of quality of life in subjects with severe negative symptoms. These results support the usefulness of SCoRS for cognitive assessment that is relevant to the everyday life of patients with schizophrenia.

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“…Los déficits en procesos específicos, como las funciones ejecutivas, también se asocian con peor calidad de vida 7 y desempeño laboral 8 .…”

Section: Introductionunclassified

Alteraciones neurocognitivas en la esquizofrenia. Análisis factorial

Gaviria

Salvat

Nadal

et al. 2017

MedUPB

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RESUMENObjetivo: el déficit en los procesos cognitivos, específicamente en el rendimiento ejecutivo, de los pacientes con esquizofrenia se ha asociado con mala adaptación social. Un modelo factorial de las funciones ejecutivas permitiría detectar la asociación entre el perfil sintomático, el deterioro de la función ejecutiva y las necesidades de rehabilitación. El objetivo de esta investigación fue identificar factores de la función ejecutiva mediante un análisis factorial de las puntuaciones tipificadas de una serie de pruebas neuropsicológicas, en un grupo de pacientes ambulatorios con diagnósticos del espectro de la esquizofrenia. Metodología: estudio factorial mediante un análisis de componentes principales (ACP) con rotación ortogonal (varimax) de 13 medidas neuropsicológicas estandarizadas. Resultados: se obtuvieron tres factores independientes: (1) flexibilidad cognitiva, (2) control de la interferencia y memoria de trabajo y (3) velocidad de procesamiento y atención, que proporcionan una medición psicométrica adecuada del desempeño ejecutivo de los pacientes estudiados. Conclusiones: el análisis revela una estructura compleja de tres dimensiones cognitivas discretas que se pueden medir con una batería de uso común en la clínica. Palabras clave: análisis factorial; función ejecutiva; trastornos del espectro de la esquizofrenia. ABSTRACT Objective:The deficit in cognitive processes, specifically in executive function of patients with schizophrenia, has been associated with poor social adaptation. A factor model of executive functions would allow for the detection of the association between the symptomatic profile, the deterioration of the executive function, and rehabilitation needs. The objective of this study was to identify factors of the executive function through factor analysis of typified scores from a series of neuropsychological tests in a group of outpatients diagnosed with schizophrenia. Methodology: Factor study through principal components analysis (PCA) with orthogonal rotation (varimax) of 13 standardized neuropsychological measures. Results: Three independent factors were obtained: (1) cognitive flexibility, (2) interference control and working memory, and (3) processing speed and attention, which provide an adequate psychometric measurement of executive function in the patients studied. Conclusions: The analysis reveals a complex structure of three discrete cognitive dimensions that can be measured with cognitive assessment tools commonly used in the hospital.

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Relationships Between Cognitive Deficits, Symptoms and Quality of Life in Schizophrenia

Cited by 97 publications

References 40 publications

Quality of life and its predictors in people with schizophrenia

Quality of life and its predictors in people with schizophrenia

Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms

Alteraciones neurocognitivas en la esquizofrenia. Análisis factorial

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