Relationships Between Gastric Accommodation and Gastrointestinal Sensations in Healthy Volunteers. A Study Using the Barostat Technique and Two- and Three-Dimensional Ultrasonography

Abstract

The origin of postprandial gastrointestinal sensations and their relation to gastric accommodation remain unclear. Our aim was to investigate the relation between antral and fundal accommodation and sensations. (A) In eight healthy volunteers fundus accommodation was measured using a barostat after a 200-ml (300-kcal) liquid nutrient. Antral area (AA) was measured using ultrasound. Data on bag volumes, AA, and sensations were assessed. (B) In another eight healthy volunteers gastric volume was measured after a 500-ml (300-kcal) liquid nutrient using 2-D/3-D ultrasound. Sensations were scored using VAS. Distal and proximal volumes were calculated from 3-D datasets. (A) Fullness was correlated with AA (r = 0.48, P = 0.002). Fullness and bag volume were not correlated. (B) Fullness was correlated with AA (r = 0.77, P < 0.001) and distal volume (r = 0.75, P < 0.001). Proximal volume was not correlated with fullness (r = 0.10, P = NS). We conclude that fullness is related to antral volume and area rather than proximal volume. The gastric antrum may play a key role in normal appetite regulation.

Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting

“…In the stomach, it can assess structural and functional abnormalities. Ultrasonography has now been used to study gastric distension/accommodation (93,94), antral contractility (95,96), mechanical deformation (strain) (97), transpyloric flow (96), and gastric emptying (98,99). Ultrasound (US) is uniquely suited for concurrently measuring antral contractility, pyloric opening, pyloric flow and perhaps gastric emptying (100,101).…”

Inyección Intragástrica De Toxina Botulínica Mediante Endoscopia, ¿una Alternativa Para El Tratamiento Para La Obesidad? Una Revisión Sistemática.

“…El mal funcionamiento de este mecanismo se ha relacionado con sensación de plenitud y saciedad precoz por una hipotética reducción en la capacidad gástrica (23).…”

Current status of functional gastrointestinal evaluation in clinical practice

“…By using several pairs of electrodes, the detection of bolus movement is possible. The reflux can further be categorised by the pH electrode into acid (pH≤ 4) or non acid (pH > 4) (reproduced with permission from Elsevier © Savarino V. Gastric volume imaging techniques using ultrasonography, (41,42) as well as single-photon emission computed tomography (43) imaging have enabled the quantitative assessment of changes in proximal stomach volume after a meal, with the assumption that any changes in proximal stomach volume after a meal reflect meal-induced gastric accommodation. Gastric magnetic resonance (MR) imaging has been used to measure gastric emptying and to evaluate gastric motor function noninvasively without exposure to radiation.…”