Relationships between platelets and inflammatory markers in rheumatoid arthritis

Milovanovic, Micha; Nilsson, E; Järemo, Petter

doi:10.1016/j.cccn.2003.12.030

Cited by 121 publications

(91 citation statements)

References 8 publications

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“…We have observed an increase in the rate of this protein in the positive control group. Similar results were obtained by Mythilypriya et al [31] and Abdin et al [32] Also, Moncada et al, [33] Milovanovic et al [34] and Klimiuk et al [35] have observed high values of CRP indicative of active inflammation in the sera of patients suffering from rheumatoid arthritis. In the preventive group we did not observe any change in the rate of the serum CRP indicating that the methanolic extract of Ajuga iva decrease its level.…”

Section: Aime Effect On the Histopathological Changessupporting

confidence: 83%

Preventive and curative effect of the methanolic extract of Ajuga iva on collagen induced arthritis in rats

Arrar¹,

Abdelwahab²,

Charef³

et al. 2013

Phcog Commn

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Section: Aime Effect On the Histopathological Changessupporting

confidence: 83%

Preventive and curative effect of the methanolic extract of Ajuga iva on collagen induced arthritis in rats

Arrar¹,

Abdelwahab²,

Charef³

et al. 2013

Phcog Commn

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“…Studies evaluating the relationship between MPV and chron� ic inflammatory disease have shown high MPV values in patients with rheumatoid arthritis in the active period of the disease with high inflammatory marker levels. 24 Similarly, MPV values decreased after treatment of active disease in patients with ankylosing spondylitis. 25 Furthermore, higher MPV values were shown in patients with severe obstructive sleep apnea leading to cardiovas� cular complications compared to a control group in a study with 95 subjects.…”

Section: Coban Et Almentioning

confidence: 95%

Does varicocele correction lead to normalization of preoperatively elevated mean platelet volume levels?

Çoban

Ibrahim

Bıyık

et al. 2015

CUAJ

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Introduction: There are several studies on the relationship between increased mean platelet volume (MPV) and varicocele. �e inves� �e inves� tigated the relationship between preoperative and 6�month post� operative MPV values in patients whose varicocele was corrected with surgery. Methods: A total of 282 patients underwent surgery at our urology clinic between December 2011 and December 2013 for primary varicocele. �e retrospectively examined the records of 61 patients who came to the 6�month postoperative follow�up. The preop� erative varicocele diagnosis was made with physical examination findings and supported with colour Doppler ultrasonography. Results: The varicocele was grade I in 12 patients, grade II in 34 patients and grade III in 11 patients. �hen the preoperative and 6�month postoperative haemoglobin (Hb), MPV, mean corpuscular volume, platelet, and platelet distribution width (PD�) values were compared, there was a significant decrease in MPV (p = 0.019), and a significant increase in Hb (p < 0.001). A noticeable increase was also present in PD�, but it was not statistically significant (p = 0.058). Conclusion: �e found that MPV increased in patients with varic� ocele and tended to decrease again after the varicocele was sur� gically corrected. However, we feel larger prospective series are needed.

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“…In conclusion, an increased MPV is shown more reactive platelets. Previous studies showed that increased in MPV is closely correlated with inflammation and to reflect inflammatory burden in different condition [6][7][8] . MPV is a parameter easily calculated by automatic blood count equipment during routine blood counts in all ED services.…”

Section: Resultsmentioning

confidence: 95%

“…An increased MPV is an indicator of larger and more reactive platelets 5 . Previous studies showed that increased mean platelet volume (MPV) is closely correlated with inflammation and to reflect inflammatory burden in different condition [6][7][8] . In our knowledge, this is the first study in the literature about the relation between SVT and MPV.…”

Section: Introductionmentioning

confidence: 99%

The importance of the mean platelet volume in the diagnosis of supraventricular tachycardia

Ocak¹,

Erdem²,

Duran³

et al. 2013

Afr H. Sci.

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Background: This retrospective study aimed to investigate the diagnostic relation between the mean platelet volume (MPV) and supraventricular tachyarrhythmia (SVT) in patient with documented atrial tachyarrhythmia in the emergency department (ED). Methods: Two study groups were compared; a SVT group with arrive at the ED with documented SVT (n=122) and 100 healthy adult without any palpitation symptom, arrhythmic disease, and with normal physical examination results that were brought for checkups to the cardiology polyclinic were classified as control group. Blood samples were obtained from all patients for determining the hematologic counts and MPV during first hour in ED period. Results: In terms of the focus of the study, hemoglobin, neutrophil count, mean cell volume (MCV), red cell distribution width (RDW), platelet, white blood cell (WBC), and lymphocyte counts were similar in both group (p>0.05). MPV in the SVT group was significantly higher than in the control group (9.12±1.22 flvs 8.64±0.89 fl, p<0.001). Multivariate logistic regression analysis showed that just MPV was independent predictor of SVT in patients with palpitation in ED (odds ratio [OR] 8.497, 95% confidence interval (6.181 to 12.325), p=0.012).Conclusions: The present study described that MPV is helpful parameter for the diagnosis of SVT in emergency department, for the first time in the literature.

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Relationships between platelets and inflammatory markers in rheumatoid arthritis

Cited by 121 publications

References 8 publications

Preventive and curative effect of the methanolic extract of Ajuga iva on collagen induced arthritis in rats

Preventive and curative effect of the methanolic extract of Ajuga iva on collagen induced arthritis in rats

Does varicocele correction lead to normalization of preoperatively elevated mean platelet volume levels?

The importance of the mean platelet volume in the diagnosis of supraventricular tachycardia

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