Release of Melanocyte-Stimulating Hormone from the Rat Posterior Pituitary Lobe Incubated in situ and from the Hypothalamus

Abstract

Experiments employing in situ incubation of the posterior pituitary lobe and washing of the pituitary stalk showed: the presence of MSH in the outflow fluid washing the posterior lobe; diminishing release of MSH from the posterior pituitary lobe into the incubating fluid with time; and that some MSH is released from the pituitary stalk or hypothalamus after removal of the posterior lobe.

Effect of Intravenous and Intracarotid Injections of Hypertonic Fluids on the Release of Melanocyte-Stimulating Hormone From the Rat Posterior Pituitary Lobe Incubated in Situ

“…according to previous results (Cyrkowicz, 1972) after 90 min of incubation. Three groups, each of ten rats, were injected into the tail vein.…”