Reliability analysis of a mini-instrument for simultaneous monitoring water content, deep tissue temperature, and hemodynamic parameters

Li, Ting; Li, Zebing; Zhao, Ke; Pan, Boan; Wang, Zhiyuan; Yang, Xiping

doi:10.1016/j.microrel.2018.05.009

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…A device based on NIRS technology was developed by our research group. Similar NIR devices have been developed and proven to be reliable and stable during the performance evaluation . The NIR device consists of three modules: the NIR probe, the controlling and processing module and a data acquisition app, showed in Figure .…”

Section: Methodsmentioning

confidence: 99%

Monte Carlo modeling of photon migration in realistic human thoracic tissues for noninvasive monitoring of cardiac hemodynamics

Liu

Chen

Fang

et al. 2019

Journal of Biophotonics

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Noninvasive monitoring of cardiac hemodynamics remains challenging in cardiovascular medicine. The possibility of noninvasive optical monitoring of cardiac hemodynamics was theoretically investigated in this study. By utilizing the Monte Carlo simulation method for voxelized media (MCVM) and Visible Chinese Human dataset, we quantified and visualized the photon migration in human thoracic region. The light fluence distribution was showed to reach heart tissue (∼3 cm depth underbody surface) and 12% of the total fluence was absorbed by the myocardium. The proportion of spatial sensitivity distribution (SSD) in cardiac tissue to the total SSD reached 0.0195%. The portion of SSD increased following with cardiac diastole and diffuse reflectance deceased linearly with increasing cardiac volume. The optimal separation between the light source and detector was provided to be 3.5 to 4.0 cm for future development of noninvasive cardiac hemodynamics monitoring. A pilot experimental study was conducted to measure the diffuse reflectance light and fingertip photoplethysmography. These data suggest that the fluctuation period of near‐infrared (NIR) diffuse reflectance was consistent with the cardiac cycle, while the fluctuation features of the NIR signal was not consistent with that of photoplethysmography. All results indicate the great potential of noninvasive optical monitoring of myocardial hemodynamics.

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Section: Methodsmentioning

confidence: 99%

Monte Carlo modeling of photon migration in realistic human thoracic tissues for noninvasive monitoring of cardiac hemodynamics

Liu

Chen

Fang

et al. 2019

Journal of Biophotonics

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“…Crosstalk is an important part of the interference signal. In previous reports [31][32][33] on a NIRS instrument independently developed by the team, the test standards for crosstalk, sensitivity and reliability were different, and the test indicators and schemes were not unified. This constitutes a hindrance to article review and significantly reduces the paper's credibility, impact and reproducibility.…”

Section: Introductionmentioning

confidence: 99%

A Novel Approach to Evaluating Crosstalk for Near-Infrared Spectrometers

Chen,

Cao,

et al. 2024

Sensors

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Multi-channel and multi-parameter near-infrared spectroscopy (NIRS) has gradually become a new research direction and hot spot due to its ability to provide real-time, continuous, comprehensive indicators of multiple parameters. However, multi-channel and multi-parameter detection may lead to crosstalk between signals. There is still a lack of benchmarks for the evaluation of the reliability, sensitivity, stability and response consistency of the NIRS instruments. In this study, a set of test methods (a human blood model test, ink drop test, multi-channel crosstalk test and multi-parameter crosstalk test) for analyzing crosstalk and verifying the reliability of NIRS was conducted to test experimental verification on a multi-channel (8-channel), multi-parameter (4-parameter) NIRS instrument independently developed by our team. Results show that these tests can be used to analyze the signal crosstalk and verify the reliability, sensitivity, stability and response consistency of the NIRS instrument. This study contributes to the establishment of benchmarks for the NIRS instrument crosstalk and reliability testing. These novel tests have the potential to become the benchmark for NIRS instrument reliability testing.

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Non-invasive optical monitoring of human lungs: Monte Carlo modeling of photon migration in Visible Chinese Human and an experimental test on a human

Guo¹,

meng²,

Su³

et al. 2022

Biomed. Opt. Express

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The human lung was quantified and visualized by photon transport in this paper. A Monte Carlo (MC) simulation of voxelized media was used with the visible Chinese human (VCH). This study theoretically explored the feasibility of non-invasive optical detection of pulmonary hemodynamics, and investigated the optimal location of the light source in the lung photon migration and optimized the source-detector distance. The light fluence intensity showed that the photon penetration depth was 6-8.4 mm in the human lung. The optimal distance from the light source to the detector was 2.7-2.9 cm, but the optimal distance of the superior lobe of right lung was 3.3-3.5 cm. We then conducted experiments on diffuse light reflectance using NIRS on 14 volunteers. These measurements agree well with the simulation results. All the results demonstrated the great potential of non-invasive monitoring of pulmonary hemodynamics and contribute to the study of human lungs in the biomedical optics community

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Reliability analysis of a mini-instrument for simultaneous monitoring water content, deep tissue temperature, and hemodynamic parameters

Cited by 4 publications

References 21 publications

Monte Carlo modeling of photon migration in realistic human thoracic tissues for noninvasive monitoring of cardiac hemodynamics

Monte Carlo modeling of photon migration in realistic human thoracic tissues for noninvasive monitoring of cardiac hemodynamics

A Novel Approach to Evaluating Crosstalk for Near-Infrared Spectrometers

Non-invasive optical monitoring of human lungs: Monte Carlo modeling of photon migration in Visible Chinese Human and an experimental test on a human

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