Reliability and validity of the Chinese version of the Patient Health Questionnaire-9 (C-PHQ-9) in patients with psoriasis: a cross-sectional study

Ye, Xin; Shu, Hui-Ling; Feng, Xia; Xia, Dengmei; Wang, Zhengqun; Mi, Wen-Yao; Yu, Bei; Zhang, Xueli; Li, Changqiang

doi:10.1136/bmjopen-2019-033211

Cited by 32 publications

(26 citation statements)

References 20 publications

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“…After exclusion of incomplete questionnaires, 326 (response rate 71%) were qualified for further analysis, including 159 patients with psoriasis (108 males and 51 females) and 167 non-psoriatic controls (84 males and 83 females). The two groups were agematched, and the differences in sex ratio (27) and BMI (28) were consistent with previous epidemiological findings. The summary of demographic and clinical details was described in Table 1.…”

Section: Higher Incidence Of Gastrointestinal Discomfort Symptoms In Patients With Psoriasis Than Common Populationsupporting

confidence: 87%

Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris

et al. 2021

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Objectives: Psoriasis is a common chronic recurrent dermatitis. Accumulating observations show gut microbiota dysbiosis in psoriasis. We intend to further investigate the relationship between intestinal microbiota and psoriasis development.Design: We first performed an epidemiological investigation on differences of gastrointestinal discomfort symptoms between patients with psoriasis and general population. Then variation of gut microbiota in patients with psoriasis (un)treated with acitretin plus narrow-band ultraviolet B (NB-UVB) was analyzed by 16S rRNA sequencing. We last compared recovery status and vital cytokines (lesion and intestine) of mouse psoriasiform models, which were transplanted with fecal microbiota from patients with psoriasis or healthy controls.Results: (1) About 85.5% of patients with psoriasis vs. 58.1% of healthy controls presented with at least one gastrointestinal symptom. The prevalence of investigated symptoms (e.g., abdominal distension and constipation) were significantly higher in patients, compared with controls (p < 0.05). Passing flatus and constipation were significantly correlated with psoriasis (p < 0.05 in both cases). (2) The abundance of Ruminococcaceae family, Coprococcus_1 genus, and Blautia genus were decreased with psoriasis improvement (p < 0.05, respectively), which had been demonstrated significantly increased in psoriasis. (3) Mice receiving psoriatic microbes transplantation showed delayed recovery of psoriasiform dermatitis and less reduction of interleukin (IL)-17A than those receiving healthy microbiota or blank control (p < 0.05 and p < 0.01, respectively).Conclusion: Multiple evidence we provided here preliminarily demonstrates the involvement of gut microbiota in the different degree of psoriasis activity. The strategy based on overall microbial communities is expected to be a promising supplementary for long-term management of psoriasis.

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Section: Higher Incidence Of Gastrointestinal Discomfort Symptoms In Patients With Psoriasis Than Common Populationsupporting

confidence: 87%

Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris

et al. 2021

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“…A recent meta-analysis showed that the sensitivity of the PHQ-9 was lower (0.77 versus 0.88) when using the MINI as the gold standard compared to semi-structured interviews [ 40 ]. In the present study, there was a strong correlation between the total scores of HAMD-17 and PHQ-9, which was consistent with previous findings [ 41 , 42 ]. These findings support the validity and feasibility of the use of PHQ-9 for assessing depression severity.…”

Section: Discussionsupporting

confidence: 93%

The validity and reliability of the PHQ-9 on screening of depression in neurology: a cross sectional study

et al. 2022

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Background This study aimed to explore the validity and reliability of the Patient Health Questionnaire-9 (PHQ-9) on screening of depression among patients with neurological disorders, and to explore factors influencing such patients. Methods In this study, 277 subjects who were admitted to the department of neurology of our hospital due to different neurological disorders completed the PHQ-9 questionnaire. The Mini-International Neuropsychiatric Interview (MINI) and Hamilton Rating Scale for Depression (HAMD) were employed to evaluate the depressive symptoms of patients who completed the PHQ-9 questionnaire. The internal consistency, criterion validity, structural validity, and optimal cut-off values of PHQ-9 were evaluated, and the consistency assessment was conducted between the depression severity as assessed by PHQ-9, HAMD and MINI. Logistic regression analysis was used to calculate the risk factors of depression. Results The Cronbach’s α coefficient of the PHQ-9 was 0.839. The Pearson’s correlation coefficient among the 9 items of the PHQ-9 scale was 0.160 ~ 0.578 (P < 0.01), and the Pearson’s correlation coefficient between each item and the total score was at the range of 0.608 ~ 0.773. Taking the results of MINI as the gold standard, the area under the receiver operating characteristic (ROC) curve of the PHQ-9 results for all the subjects (n = 277) was 0.898 (95% confidence interval (CI): 0.859 ~ 0.937, P < 0.01). When the cut-off score was equal to 5, the values of sensitivity, specificity, and the Youden’s index were 91.2, 76.6%, and 0.678, respectively. Multivariate logistic regression analysis showed that the influence of unemployment on the occurrence of depression was statistically significant (P = 0.027, OR = 3.080, 95%CI: 1.133 ~ 8.374). Conclusions The application of PHQ-9 for screening of depression among Chinese patients with neurological disorders showed a good reliability and validity.

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“…The total score of the scale is 27 points, higher than 5 points indicate mild depression, higher than 10 points indicate moderate depression, and higher than 15 points indicate severe depression. The Chinese version of PHQ-9 has been validated in previous studies (α = 0.94) [19].…”

Section: Psychosomatics Factorsmentioning

confidence: 99%

Prevalence of PTSD Symptoms Among Psychiatric Patients During the COVID-19 Pandemic

Tang

Gao

et al. 2021

Preprint

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Background: The outbreak of the COVID-19 pandemic has caused extensive public health concern and posed great challenges to the medical services, including the mental health concern for psychiatric patients who were one of neglected groups. The current study aimed to assess the prevalence and risk factors of post-traumatic stress disorder (PTSD) symptoms among psychiatric patients in China during the pandemic. Method: Self-reported questionnaires were distributed to psychiatric patients in several psychiatric hospitals in Beijing China from 28 April to 30 May 2020. The socio-demographic information and psychiatric symptoms such as PTSD, anxiety and depressive symptoms were collected by using The Impact of Event Scale- Revised (IES-R), the 7-item Generalized Anxiety Disorder Scale (GAD-7) and the 9-item Patient Health Questionnaire depression scale (PHQ-9). Multivariate regression was used to analysis the related factors for PTSD symptoms. Results: 1,055 psychiatric patients were included in the final sample. The prevalence of PTSD symptoms was 41.3%. Risk factors for PTSD symptoms and its subscales included old age, high risk perception, symptoms of anxiety, symptoms of depression. Conclusions: The prevalence of PTSD symptoms is high among psychiatric patients during the COVID-19 pandemic in China. We call for more concern and PTSD interventions to relieve the psychological stress of psychiatric patients during the pandemic.

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Reliability and validity of the Chinese version of the Patient Health Questionnaire-9 (C-PHQ-9) in patients with psoriasis: a cross-sectional study

Cited by 32 publications

References 20 publications

Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris

Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris

The validity and reliability of the PHQ-9 on screening of depression in neurology: a cross sectional study

Prevalence of PTSD Symptoms Among Psychiatric Patients During the COVID-19 Pandemic

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