Reliability of transcranial colour-coded real-time sonography in assessment of brain tumours: correlation of ultrasound, computed tomography and biopsy findings

Becker, Georg; Krone, A.; Koulis, D.; Lindner, Alfred; Hofmann, Erich; Roggendorf, Wolfgang; Bogdahn, Ulrich

doi:10.1007/bf00600414

Cited by 49 publications

(35 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The peri-operative morbidity and mortality, in the literature between 0% [80] and 16% [2], was not higher due to the biopsies in comparison to other series [24]. For transcranial sonography the correlation between CT or MRI, histological and sonographic findings of residual tumour and tumour regrowth has been shown for children [21,36,37,84] and recently for adults [6,7,47]. In another ongoing study (authors) a correlation between IOUS and early postoperative CT/MRI and histological findings of tumour remnants will be done.…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

Correlation of intra-operative ultrasound with histopathologic findings after tumour resection in supratentorial gliomas

et al. 1996

Self Cite

View full text Add to dashboard Cite

The aim of this study was to evaluate whether intra-operative ultrasound (= IOUS) is a suitable tool to detect residual tumour tissue after gross total resection in supratentorial gliomas. During a period of 18 months 45 patients with supratentorial gliomas (38 high-grade and 9 low-grade, according to the WHO-grading system [42]) were operated on. A series of 78 biopsies was taken from the resection cavity under continuous sonographic control at the end of surgery. Gross total tumour resection was intended in 34 patients (= 76%). The biopsy specimens were matched with the sonographic features at each biopsy site. The sonographic appearance of the resection margins were classified into 2 groups: (1) Irregular hyperechoic areas extending from the cavity into the iso-echogenic brain tissue and (2) a dense small (< or = 3 mm in diameter) rather regular hyperechoic rim surrounding the resection cavity. 47 out of 53 biopsies taken from hyperechoic areas (group I) (36 high-grade/11 low-grade) revealed solid tumour tissue (= 89%). 34 (= 72%) of these 47 areas were microscopically assessed as inconspicuous by the surgeon. 6 samples (4 high-grade/2 low-grade) contained tumour infiltration zone. 25 biopsies (23 high-grade/2 low-grade) taken from the hyperechoic rim [group 2] were diagnosed as follows: Normal brain tissue in 11, tumour infiltration zone in 8 and solid tumour tissue in 6 cases. Of 34 cases with "gross total removal" according to the surgeon's assessment 25 showed sonographic signs of residual tumour tissue, which was confirmed histologically as solid tumour tissue in 22 of these cases. It is concluded, that IOUS following resection of supratentorial gliomas can detect residual tumour tissue with high specificity and thus improve gross total resection. However, a thin hyperechoic rim surrounding the resection cavity (less than 3 mm in diameter) is a non-specific finding, which can mask thin residual tumour layers and therefore needs further evaluation of its nature.

show abstract

Section: Discussionmentioning

confidence: 95%

“…Ultrasound has shown intra-operatively [5,8,11,15,22,26,30,32,48,50,59,61,62,64,66,73,76,79,81] and transcranially [6,9,10,17,69,75,77] to be a reliable real-time method in the delineation of tumour tissue before resection, even superior to contrast-enhanced CT or MRI [35,43,47].…”

Section: Introductionmentioning

confidence: 99%

Correlation of intra-operative ultrasound with histopathologic findings after tumour resection in supratentorial gliomas

et al. 1996

Self Cite

View full text Add to dashboard Cite

show abstract

“…This approach gives us the opportunity to learn even more about brain tumor imaging and the most eVective approach in serial stereotactic biopsy. Similar studies correlating transcranial color-coded real-time ultrasound and computed tomography with biopsy characteristics or combining stereo-EEG, CT and morphology showed a correlation between imaging and morphology (Becker et al 1994;Munari et al 1985).…”

Section: Discussionmentioning

confidence: 71%

Multiplanar MRI–CT fusion neuronavigation-guided serial stereotactic biopsy of human brain tumors: proof of a strong correlation between tumor imaging and histopathology by a new technical approach

Kuhn

Romeike

Walter

et al. 2009

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

show abstract

“…1,2,6 -8 Furthermore, the temporal bone window allows the identification of parenchymal abnormalities such as intracerebral hemorrhage, tumors, and pathology of the ventricular system. [3][4][5] However, because of the unfavorable insonation angle, measurements of flow velocities of the A2 segment of the ACA, the PCoA, and the venous midline vasculature are often unreliable. The same difficulties apply to imaging of the frontal parenchyma.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 New aspects of TCCS are assessment of the brain parenchyma [3][4][5] and intracranial veins and sinuses. 6 -8 The standard approach is insonation through a temporal bone window.…”

mentioning

confidence: 99%

Frontal Bone Windows for Transcranial Color-Coded Duplex Sonography

Stolz

Kaps

Kern

et al. 1999

Stroke

View full text Add to dashboard Cite

Background and Purpose-The use of the conventional temporal bone window for transcranial color-coded duplex sonography (TCCS) often results in difficulties in obtaining angle-corrected flow velocity measurements of the A2 segment of the anterior cerebral artery, the posterior communicating artery, and the midline venous vasculature because of the unfavorable insonation angle. The same applies to B-mode imaging of the frontal parenchyma. However, transorbital TCCS raises problems with the insonation of the orbital lens. To overcome these drawbacks, we studied the feasibility of frontal bone windows for TCCS examinations. Methods-In 75 healthy volunteers (mean age, 45.3Ϯ17.0 years; age range, 17 to 77 years), the circle of Willis and the venous midline vasculature were insonated through a lateral and paramedian frontal bone window. Insonation quality of parenchymal structures (B-mode) was graded on a 3-point scale depending on the visibility of typical parenchymal landmarks. In a similar manner, the quality of the color-/Doppler-mode imaging of the arteries of the circle of Willis and the internal cerebral veins was assessed. In 15 patients (mean age, 62.7Ϯ13.7 years; age range, 33 to 83 years), the color-/Doppler-mode imaging quality of the intracranial vessels before and after application of an ultrasound contrast-enhancing agent was compared. Results-B-mode insonation quality was optimal to fair in 73.3% of cases using the lateral and in 52.0% of cases using the paramedian frontal bone window, with defined parenchymal structures used as reference. Insonation quality decreased in those older than 60 years. In those younger than 60 years, angle-corrected flow velocity measurements of the A2 segment of the anterior cerebral artery and the internal cerebral vein were possible in 73.6% and 60.0%, respectively. Contrast enhancement resulted in a highly significant improvement in the imaging quality of the intracranial vessels. Conclusions-The transfrontal bone windows offer new possibilities for TCCS examinations, although the insonation quality is inferior to the conventional temporal bone window in terms of failure of an acoustic window. This can be compensated for by application of an ultrasound contrast-enhancing agent. (Stroke. 1999;30:814-820.)

show abstract

Reliability of transcranial colour-coded real-time sonography in assessment of brain tumours: correlation of ultrasound, computed tomography and biopsy findings

Cited by 49 publications

References 15 publications

Correlation of intra-operative ultrasound with histopathologic findings after tumour resection in supratentorial gliomas

Correlation of intra-operative ultrasound with histopathologic findings after tumour resection in supratentorial gliomas

Multiplanar MRI–CT fusion neuronavigation-guided serial stereotactic biopsy of human brain tumors: proof of a strong correlation between tumor imaging and histopathology by a new technical approach

Frontal Bone Windows for Transcranial Color-Coded Duplex Sonography

Contact Info

Product

Resources

About