2009
DOI: 10.1590/s0365-05962009000100013
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Remissão de lentigo maligno extenso após tratamento com imiquimod

Abstract: Lentigo maligno é um melanoma in situ que mais comumente surge em áreas expostas à radiação ultravioleta, nos pacientes idosos. O tratamento é realizado, principalmente, para minimizar o risco de progressão para lentigo maligno melanoma. O presente relato se refere a uma paciente idosa com lesões recorrentes de lentigo maligno na face, tratada com sucesso com imiquimod tópico, mostrando que este pode ser um tratamento útil, em determinados casos da doença.

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Cited by 6 publications
(2 citation statements)
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“…In these particular cases, there are other alternative treatment options, such as imiquimod, a synthetic compound of the imidazoquinoline family, a topical immune response modifier. 5 By binding to tolllike receptors 7 and 8 of dendritic cells, imiquimod stimulates the production of cytokines (INF-alpha, IL12, TNF-alpha, IL2, INF-gamma, etc. ), lymphocyte activation in the the regional lymph node with production of CD8 T lymphocytes and induction of apoptosis.…”
Section: Commentsmentioning
confidence: 99%
“…In these particular cases, there are other alternative treatment options, such as imiquimod, a synthetic compound of the imidazoquinoline family, a topical immune response modifier. 5 By binding to tolllike receptors 7 and 8 of dendritic cells, imiquimod stimulates the production of cytokines (INF-alpha, IL12, TNF-alpha, IL2, INF-gamma, etc. ), lymphocyte activation in the the regional lymph node with production of CD8 T lymphocytes and induction of apoptosis.…”
Section: Commentsmentioning
confidence: 99%
“…and B -Professor Sebastião de Almeida Prado Sampaio, days before his death, manifested the desire of once more cooperating with the Brazilian Annals of Dermatology (Anais Brasileiros de Dermatologia -ABD) by means of this publication 60. …”
mentioning
confidence: 99%