Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) associated with psoriatic arthritis

Kardeş, Sinan; Karagülle, Mine; Erdoğan, Nusret

doi:10.3109/03009742.2015.1020069

Cited by 6 publications

(2 citation statements)

References 4 publications

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“…RS3PE has not been proven to be a variant of PMR but does share some similarities such as presentation in an elderly population, abrupt onset, symmetrical manifestations and a good responses to low-dose glucocorticoid therapy 29. RS3PE occurrence with gout and psoriatric arthritis has also been reported 30 31…”

Section: Discussionmentioning

confidence: 79%

Remitting Seronegative Symmetrical Synovitis with Pitting Edema: A Review

Lakhmalla

Dahiya

Kichloo

et al. 2021

Journal of Investigative Medicine

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Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare benign rheumatological condition characterized by sudden-onset symmetrical distal extremity edema. It can present as an isolated disease process or could be associated with other conditions. Rheumatoid factor and anticitrullinated protein antibodies are negative by definition. In current literature, there is paucity of data about the disease process. We performed a literature search using the PubMed database to identify 38 articles that met our inclusion and exclusion criteria. Our literature review focuses on the clinical picture and its diverse associations. Role of various acute phase reactants has also been outlined. There is a generalized consensus among clinicians on using moderate dose steroids for treatment. Other management options for refractory cases have also discussed. Value of several imaging modalities in diagnostic evaluation of this disease entity is touched on. Since RS3PE can be associated with other diseases, specifically cancer, timely diagnosis of this condition is necessary.

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Section: Discussionmentioning

confidence: 79%