Remodeling of Extracellular Matrix Patch used for Carotid Artery Repair

Extracellular Matrix Scaffold as a Tubular Graft for Ascending Aorta Aneurysm Repair

“…Unexpectedly, our histological examination indicated no stem cell factor, no endothelial cell ingrowth, and almost identical morphology compared to a brand new CorMatrix sheet. This was contrary to the previous literature which described cellular remodeling postimplantation for arterial reconstruction . In our sample, there was trace vascular remodeling, but not enough to demarcate our patient sample as a fully infiltrated and transformed scaffold.…”

“…This was contrary to the previous literature which described cellular remodeling postimplantation for arterial reconstruction. 2 In our sample, there was trace vascular remodeling, but not enough to demarcate our patient sample as a fully infiltrated and transformed scaffold. We suspect that lack of cellular finding in our patient specimen may have been due to the location and tissue explanted at the time of surgery.…”

Evaluation of Explanted CorMatrix Intracardiac Patches in Children With Congenital Heart Disease

“…Early animal studies of SIS products were encouraging [1,[8][9][10][11][12]. Badylak and colleagues [1] used circular patches created from sheets of ECM derived from porcine small intestinal submucosa or porcine urinary bladder matrix to repair full-thickness defects of the right ventricular anterior walls of six pigs.…”

Utilization of a Tubularized CorMatrix Extracellular Matrix for Repair of an Arteriovenous Fistula Aneurysm

“…Animal research has demonstrated that this material remains durable during phases from initial implantation throughout regeneration in carotid artery repairs. 3 Early experiences with clinical utilization in aortoinnominate disruption 5 and cardiac valve repair 6,7 also speak to the ability of CorMatrix ECM to well tolerate the comparatively lower pressure thresholds encountered in peripheral AVF reconstruction.…”